{"id":"W2139001568","doi":"10.6000/1927-5951.2014.04.04.4","title":"Improved Serotonergic Tone Contributes to the Mechanism of Action of St John’s Wort in Nicotine Withdrawn Mice","year":2014,"lang":"en","type":"article","venue":"Journal of Pharmacy and Nutrition Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Nicotine; Serotonergic; Corticosterone; Chemistry; Saline; Serotonin; Pharmacology; Abstinence; 5-Hydroxyindoleacetic acid; Internal medicine; Endocrinology; Medicine; Biochemistry; Psychiatry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001118707,0.0005514948,0.0004641177,0.0003918142,0.0001620378,0.0002322974,0.0002768048,0.0004557981,0.0014752],"category_scores_gemma":[0.0001167218,0.0002299211,0.0004723704,0.0001160967,0.0003481081,0.000276743,0.0001738154,0.0009373611,0.0002394984],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002391381,"about_ca_system_score_gemma":0.0002160911,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009777322,"about_ca_topic_score_gemma":0.002426205,"domain_scores_codex":[0.9998919,0.00001432368,0.00001148881,0.00002500909,0.00003213437,0.00002513827],"domain_scores_gemma":[0.9998691,0.000008706548,0.00005143754,0.00001099826,0.00001151614,0.00004817257],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006432521,0.0001926081,0.0007463872,0.00008063323,0.00001958285,0.0002439278,0.00002114362,0.00002035184,0.9957286,0.00003173087,0.00003333161,0.00223846],"study_design_scores_gemma":[0.0003042544,0.01337616,0.0944548,0.00006292497,0.0001862282,0.002073685,0.0002268926,0.001153456,0.8852866,0.0001776737,0.002670643,0.00002670302],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969273,0.001656491,0.0005678898,0.0001351824,0.00002700969,0.00002525916,0.0001583875,0.00003276293,0.0004698445],"genre_scores_gemma":[0.9938198,0.002230211,0.0008222472,0.0001113011,0.00002511811,0.00005077202,0.0003305316,0.0000104791,0.002599605],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0014752,"threshold_uncertainty_score":0.004934967,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0388499978309111,"score_gpt":0.3402481649169039,"score_spread":0.3013981670859928,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}