{"id":"W2139059185","doi":"10.3389/fneur.2014.00167","title":"Aluminum-Induced Amyloidogenesis and Impairment in the Clearance of Amyloid Peptides from the Central Nervous System in Alzheimerâ€™s Disease","year":2014,"lang":"en","type":"review","venue":"Frontiers in Neurology","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Surrey Place Centre; University of Toronto","funders":"National Eye Institute; National Institute on Aging; National Institutes of Health; Louisiana Biomedical Research Network; Research to Prevent Blindness","keywords":"Neurodegeneration; Neuroscience; Disease; Amyloid (mycology); Central nervous system; Medicine; Alzheimer's disease; Pathology; Psychology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006227285,0.0009250935,0.001481946,0.001875352,0.0002136112,0.0008079835,0.0007511782,0.001128062,0.001821263],"category_scores_gemma":[0.0005007781,0.0002380112,0.0004726782,0.001941055,0.0005829642,0.001072243,0.0006175334,0.001180504,0.001450802],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005746552,"about_ca_system_score_gemma":0.0008077141,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007658358,"about_ca_topic_score_gemma":0.001670894,"domain_scores_codex":[0.9998751,0.00002517287,0.00002342437,0.00001841732,0.00004468323,0.0000131005],"domain_scores_gemma":[0.9997926,0.0000718532,0.00005442884,0.000006556295,0.0000567461,0.00001776725],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001971134,0.00006722244,0.0002488719,0.0235154,0.0001970116,0.0003072121,0.00005305853,0.0002652573,0.003002431,0.00196795,0.02323269,0.9469458],"study_design_scores_gemma":[0.0001522548,0.0003268545,0.003927727,0.01215435,0.0006674843,0.005779243,0.0001691552,0.0001946749,0.002268204,0.007026804,0.9672742,0.00005902292],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009073429,0.9993804,0.00005457731,0.0001370244,0.000066552,0.000001685103,0.000006868609,0.000004941733,0.000257254],"genre_scores_gemma":[0.0007822777,0.9987487,0.0000832342,0.0001031335,0.00007121251,0.000003165223,0.0000114219,6.198798e-7,0.0001962251],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001875352,"threshold_uncertainty_score":0.006092668,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03046318079326621,"score_gpt":0.2981194646559557,"score_spread":0.2676562838626895,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}