{"id":"W2139062539","doi":"10.1152/ajplung.00328.2014","title":"Arginase inhibition prevents bleomycin-induced pulmonary hypertension, vascular remodeling, and collagen deposition in neonatal rat lungs","year":2015,"lang":"en","type":"article","venue":"American Journal of Physiology-Lung Cellular and Molecular Physiology","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"Heart and Stroke Foundation; University of Toronto; Health Sciences North; SickKids Foundation; Lakehead University; NOSM University; Hospital for Sick Children","funders":"Canadian Institutes of Health Research","keywords":"Arginase; Bleomycin; Nitric oxide; Pulmonary hypertension; Lung; Nitric oxide synthase; Medicine; Internal medicine; Endocrinology; Pharmacology; Arginine; Chemistry; Biochemistry; Amino acid; Chemotherapy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002758027,0.000444995,0.0005153102,0.0003124767,0.000138395,0.0002319455,0.0002961609,0.0003182552,0.0009778822],"category_scores_gemma":[0.0002919437,0.000169167,0.0002314113,0.0001030512,0.0004140745,0.0003080853,0.0001756248,0.0009668781,0.0002265499],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002351053,"about_ca_system_score_gemma":0.0003864539,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007636237,"about_ca_topic_score_gemma":0.001453601,"domain_scores_codex":[0.9998293,0.0000375856,0.00002044901,0.00002731973,0.00003798729,0.00004728578],"domain_scores_gemma":[0.999508,0.00008030397,0.0001601965,0.00004651411,0.00003792785,0.000167103],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008042055,0.0001672692,0.0002247859,0.00004261631,0.00000699962,0.00009169656,0.00002261519,0.00007107418,0.9966412,0.0000633114,0.0000283658,0.001835938],"study_design_scores_gemma":[0.00005010587,0.001813953,0.003795268,0.000009404885,0.00001795602,0.000198025,0.00004419003,0.000434117,0.9930676,0.00003828233,0.0005255326,0.000005541743],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959527,0.001575364,0.001589932,0.00009582843,0.00003922583,0.00002175222,0.0001412172,0.00007590476,0.0005081385],"genre_scores_gemma":[0.9940234,0.001439209,0.001812806,0.00005259678,0.00002146247,0.00004870507,0.0002750969,0.00002426124,0.002302554],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009778822,"threshold_uncertainty_score":0.003271341,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00830387951125672,"score_gpt":0.2320301227226377,"score_spread":0.223726243211381,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}