{"id":"W2139077852","doi":"10.1007/s00592-004-0165-8","title":"Re-institution of good metabolic control in diabetic rats and activation of caspase-3 and nuclear transcriptional factor (NF-kB) in the retina","year":2004,"lang":"en","type":"article","venue":"Acta Diabetologica","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":85,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"Foundation for the National Institutes of Health","keywords":"Diabetes mellitus; Internal medicine; Endocrinology; Diabetic retinopathy; Apoptosis; Caspase 3; Streptozotocin; Retina; Glycated hemoglobin; Chemistry; Biology; Medicine; Type 2 diabetes; Biochemistry; Programmed cell death","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000996954,0.0001017466,0.0003164158,0.00008281069,0.00002903942,0.000006171485,0.00004251613,0.00007042435,0.00002291997],"category_scores_gemma":[0.0001087933,0.00006406855,0.00004417416,0.0001398063,0.0001417572,0.00008586855,0.000007683632,0.00009513769,5.406501e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001959086,"about_ca_system_score_gemma":0.00003057855,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001160261,"about_ca_topic_score_gemma":0.0000192521,"domain_scores_codex":[0.9992665,0.00007861499,0.0002248359,0.0001576334,0.0001429161,0.0001294925],"domain_scores_gemma":[0.9996337,0.00009528912,0.00008802072,0.0001122411,0.00002754536,0.00004326124],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001013605,0.001729538,0.831924,0.0002369222,0.0001313543,0.00005516478,0.002070981,0.00001717252,0.1470733,0.0130052,0.00001017726,0.002732608],"study_design_scores_gemma":[0.003235293,0.0003989399,0.9928464,0.0001236422,0.0000988203,0.000004627212,0.0003578844,0.00003384181,0.002075503,0.0006998713,0.00007080838,0.00005434227],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969046,0.0006762777,0.000005741781,0.001490677,0.00001302159,0.00045387,0.00003655336,0.00000637009,0.0004129101],"genre_scores_gemma":[0.9993463,0.0003368277,0.0000633313,0.0002018099,0.000008864191,0.00001995919,0.00001631853,0.000004878002,0.000001680868],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1609224,"threshold_uncertainty_score":0.261264,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01739862761776365,"score_gpt":0.2531121433158501,"score_spread":0.2357135156980864,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}