{"id":"W2139093684","doi":"10.1158/1078-0432.ccr-08-1159","title":"Phase II Trial of OGX-011 in Combination with Docetaxel in Metastatic Breast Cancer","year":2009,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Clusterin in disease pathology","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research; Juravinski Cancer Centre; Ottawa Regional Cancer Foundation; BC Cancer Agency; Ottawa Hospital; University of British Columbia","funders":"","keywords":"Docetaxel; Metastatic breast cancer; Clusterin; Medicine; Breast cancer; Internal medicine; Regimen; Chemotherapy; Cancer; Oncology; Apoptosis; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008835151,0.001410158,0.001851774,0.0003667717,0.0003463053,0.0007740411,0.0009292903,0.001090013,0.003441417],"category_scores_gemma":[0.0005998545,0.0004606955,0.0007408342,0.0004094084,0.0009085256,0.0003803631,0.0003180247,0.002132948,0.0007154291],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001005855,"about_ca_system_score_gemma":0.001918026,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001067003,"about_ca_topic_score_gemma":0.00308385,"domain_scores_codex":[0.9996996,0.0001365996,0.0000156409,0.00004664586,0.00003468986,0.00006691404],"domain_scores_gemma":[0.9995307,0.00006569976,0.00009744713,0.00002616378,0.00002202598,0.000257931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7430277,0.07633883,0.006082912,0.001269157,0.0008419062,0.0004602519,0.0003117244,0.003609446,0.0455703,0.000396189,0.00455119,0.1175404],"study_design_scores_gemma":[0.5883034,0.3973491,0.005694398,0.00004918684,0.000233609,0.0003418461,0.00004745651,0.00110493,0.004171414,0.0001028196,0.002582091,0.00001969551],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937236,0.001669618,0.0002760288,0.0003525072,0.0001034462,0.00210075,0.0003529882,0.00006268303,0.001358414],"genre_scores_gemma":[0.9881924,0.002034603,0.001353904,0.0004996868,0.0001442547,0.003063098,0.001557838,0.00002179096,0.003132432],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003441417,"threshold_uncertainty_score":0.0115127,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2940175623616857,"score_gpt":0.5994853272054937,"score_spread":0.3054677648438081,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}