{"id":"W2139191475","doi":"10.1128/aac.49.8.3222-3227.2005","title":"Ciprofloxacin Induction of a Susceptibility Determinant in <i>Pseudomonas aeruginosa</i>","year":2005,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":159,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Genome Prairie; Canadian Institutes of Health Research; Genome British Columbia","keywords":"Ciprofloxacin; Pseudomonas aeruginosa; Microbiology; Biology; ORFS; Antibiotics; Bacteria; Antibiotic resistance; Bacteriophage; Minimum inhibitory concentration; Mutant; Gene; Open reading frame; Genetics; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001302094,0.0001373735,0.0001803639,0.00003753844,0.00003075759,0.00001267303,0.0001040567,0.0001322302,0.00003396651],"category_scores_gemma":[0.000008479615,0.0001273615,0.0000550256,0.00007093017,0.0001253017,0.000008567827,0.00003855136,0.00006085246,0.000002319954],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001336675,"about_ca_system_score_gemma":0.0000270215,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005010912,"about_ca_topic_score_gemma":0.0001679756,"domain_scores_codex":[0.9991443,0.0000317518,0.0002684294,0.0003060038,0.00006120293,0.0001882841],"domain_scores_gemma":[0.9996077,0.000003558712,0.00009845796,0.0002232667,0.00003196405,0.00003505524],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001629663,0.0001420496,0.2000445,0.000026842,0.00001397791,0.000001094743,0.00009743309,0.000003032403,0.785778,0.000005981094,0.002073138,0.01165095],"study_design_scores_gemma":[0.001054218,0.00009676384,0.298131,0.00003694733,0.000005162243,0.000008870819,0.00003243258,0.00001269612,0.6843432,0.00001128335,0.01610849,0.000158974],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989742,0.00003919197,0.0001046428,0.0004657285,0.00007289855,0.0001761683,0.00001051498,0.000005119901,0.0001515399],"genre_scores_gemma":[0.9967195,0.0008913784,0.001047177,0.0009512844,0.0001312386,0.000001686749,0.00002259031,0.00001630522,0.0002188763],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1014349,"threshold_uncertainty_score":0.519365,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008832151746499876,"score_gpt":0.250935686665624,"score_spread":0.2421035349191242,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}