{"id":"W2139214771","doi":"10.1158/0008-5472.can-06-4442","title":"DNA Double-Strand Breaks Form in Bystander Cells after Microbeam Irradiation of Three-dimensional Human Tissue Models","year":2007,"lang":"en","type":"article","venue":"Cancer Research","topic":"Effects of Radiation Exposure","field":"Medicine","cited_by":232,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Lethbridge","funders":"National Cancer Institute; National Institutes of Health; National Institute of Biomedical Imaging and Bioengineering; U.S. Department of Energy","keywords":"Bystander effect; Genome instability; Apoptosis; DNA damage; DNA; Biology; Molecular biology; Cell biology; Cancer research; Chemistry; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002786756,0.0003536122,0.0002289607,0.0003340342,0.0001293676,0.0002571707,0.0002184852,0.0003340944,0.001255168],"category_scores_gemma":[0.0001569744,0.0002357828,0.0003661813,0.0002255694,0.0001695785,0.0001728309,0.0002511291,0.0004688473,0.0004148328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001864736,"about_ca_system_score_gemma":0.0001619718,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001084913,"about_ca_topic_score_gemma":0.001036509,"domain_scores_codex":[0.9998379,0.00003354036,0.00001390561,0.00004417618,0.00005084783,0.00001956494],"domain_scores_gemma":[0.9998455,0.00003130207,0.00004288458,0.00003817017,0.000018766,0.00002332335],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000104845,0.00003668897,0.0004904243,0.00004422285,0.00001308314,0.0001578083,0.00007812474,0.0006648048,0.9971461,0.0001207373,0.00003189292,0.001111355],"study_design_scores_gemma":[0.00001414421,0.000878055,0.006777659,0.000008885916,0.00003807377,0.0007908082,0.00005969971,0.003752921,0.985098,0.0001127903,0.002458749,0.00001028262],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9738858,0.002780784,0.02110904,0.00005255282,0.00003087206,0.00009295859,0.0004153731,0.0001565536,0.001476187],"genre_scores_gemma":[0.984379,0.001333697,0.01010923,0.00003475777,0.000009737936,0.0001390445,0.0009101928,0.00003208955,0.003052367],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001255168,"threshold_uncertainty_score":0.004198909,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05725440081832427,"score_gpt":0.3956075018542927,"score_spread":0.3383531010359684,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}