{"id":"W2139262527","doi":"10.7150/ijbs.3.225","title":"MCEF is localized to the nucleus by protein sequences encoded within three distinct exons, where it represses HIV-1 Tat-transactivation of LTR-directed transcription","year":2007,"lang":"en","type":"article","venue":"International Journal of Biological Sciences","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; Toronto Metropolitan University","funders":"Natural Sciences and Engineering Research Council of Canada; University of Guelph","keywords":"Biology; Transactivation; Genetics; Exon; Nuclear localization sequence; Gene; In silico; Transcription factor; Fusion protein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001041346,0.0003452231,0.0002070361,0.0003278721,0.0003277127,0.0003472445,0.0001772185,0.0003623553,0.001670428],"category_scores_gemma":[0.0001860273,0.0001432365,0.0003319337,0.0002328575,0.0003018211,0.0002989279,0.0002112455,0.0003150859,0.0006855266],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004839155,"about_ca_system_score_gemma":0.0002637274,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000808203,"about_ca_topic_score_gemma":0.001105294,"domain_scores_codex":[0.9998976,0.00001098746,0.000008698346,0.00003771118,0.00002878277,0.0000162062],"domain_scores_gemma":[0.9998846,0.00003365029,0.00003650356,0.00001324836,0.00001009776,0.000021916],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001274935,0.00001082706,0.001187608,0.00005487373,0.000007052605,0.0002270861,0.00004513096,0.0001270752,0.9946191,0.0003385869,0.00006310688,0.003192127],"study_design_scores_gemma":[0.00001609231,0.00009226883,0.02154684,0.00003128813,0.00002445666,0.001784008,0.00008338013,0.002048518,0.9597051,0.0002243772,0.0144314,0.00001226884],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874036,0.00195419,0.007940426,0.0001179819,0.00001948686,0.00002717069,0.001146111,0.0001253293,0.001265585],"genre_scores_gemma":[0.9853799,0.0006357519,0.009190874,0.00005015793,0.000008454414,0.00001978848,0.002275184,0.0000269081,0.002413031],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001670428,"threshold_uncertainty_score":0.005588114,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02075639331726484,"score_gpt":0.2780444302264108,"score_spread":0.257288036909146,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}