{"id":"W2139316688","doi":"10.1186/1742-4690-11-17","title":"Direct non-productive HIV-1 infection in a T-cell line is driven by cellular activation state and NFκB","year":2014,"lang":"en","type":"article","venue":"Retrovirology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"AIDS Vancouver; University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; University of British Columbia","keywords":"Human immunodeficiency virus (HIV); Cell culture; Antibody; Virology; Medicine; NF-κB; State (computer science); NFKB1; Computational biology; Immunology; Cell biology; Biology; Computer science; Inflammation; Genetics; Transcription factor; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000207258,0.0001475214,0.000255467,0.0001654999,0.00008730975,0.000007656846,0.00005895339,0.0001991735,0.0001886102],"category_scores_gemma":[0.00007259411,0.0001316623,0.00003321161,0.0001198624,0.0001589032,0.00007865442,0.00005585986,0.0002884158,0.0008377304],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007047163,"about_ca_system_score_gemma":0.00002523556,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004216009,"about_ca_topic_score_gemma":0.00005418556,"domain_scores_codex":[0.998729,0.0003177579,0.000169607,0.0003955697,0.00002943524,0.0003586607],"domain_scores_gemma":[0.9995418,0.0001202082,0.00007515753,0.0001979769,0.0000338297,0.00003104269],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002571162,0.0002287438,0.1136571,0.00001661102,0.00006667162,0.000003375359,0.0003525417,0.00001432374,0.8779294,0.000006881614,0.003534402,0.00393289],"study_design_scores_gemma":[0.003341753,0.001770247,0.08905075,0.000009905722,0.00002233709,0.000007515791,0.00001183144,0.0000985677,0.8801216,0.0001191996,0.02526742,0.0001788061],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964126,0.0003438012,0.001053404,0.0005497726,0.00009973474,0.000266675,0.00005380303,0.00002248612,0.001197675],"genre_scores_gemma":[0.9956583,0.0002935752,0.00003081958,0.0001228327,0.0000259839,0.00004193177,0.0002584937,0.00001350259,0.003554553],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02460633,"threshold_uncertainty_score":0.9999402,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006102327566856211,"score_gpt":0.2248175382753979,"score_spread":0.2187152107085417,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}