{"id":"W2139336144","doi":"10.1081/ddc-52070","title":"Hydroxyzine- and Cetirizine-Loaded Liposomes: Effect of Duration of Thin Film Hydration, Freeze-Thawing, and Changing Buffer pH on Encapsulation and Stability","year":2005,"lang":"en","type":"article","venue":"Drug Development and Industrial Pharmacy","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Hydroxyzine; Liposome; Cetirizine; Chromatography; Chemistry; Phosphatidylcholine; Vesicle; Dosage form; Lecithin; Membrane; Pharmacology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001312675,0.0003006855,0.0004039953,0.000229593,0.0002625776,0.00002208266,0.00008071688,0.0001763234,0.0001807047],"category_scores_gemma":[0.000131439,0.0002751657,0.00002922147,0.0001866782,0.0002500799,0.0004472814,0.00009161989,0.0004686498,0.000002149441],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004989785,"about_ca_system_score_gemma":0.00006262839,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001722272,"about_ca_topic_score_gemma":0.000007406365,"domain_scores_codex":[0.9980003,0.0004076202,0.0006861467,0.0003907324,0.0002253297,0.0002899049],"domain_scores_gemma":[0.9988706,0.0005207783,0.000288645,0.00009700323,0.00006927498,0.0001536778],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005287751,0.0005807091,0.1634511,0.0008631722,0.0006755802,0.000009043535,0.03552184,0.001147528,0.4607667,0.000329592,0.001384495,0.3299825],"study_design_scores_gemma":[0.008070786,0.0001499878,0.00247034,0.00009176089,0.0001558868,0.000005310043,0.0001902266,0.01125208,0.9636598,0.00003416303,0.01362479,0.000294846],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967657,0.0009759557,0.00006714882,0.0006360268,0.000321686,0.0008791651,0.00003570412,0.00003334452,0.0002852693],"genre_scores_gemma":[0.9984442,0.0006537259,0.0001963681,0.0002270849,0.0002412113,0.00003778324,0.00007246657,0.00001759034,0.0001095825],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5028931,"threshold_uncertainty_score":0.9999701,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0852287872600691,"score_gpt":0.3662089091977411,"score_spread":0.280980121937672,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}