{"id":"W2139365621","doi":"10.1128/jvi.02299-05","title":"Modulation of Kaposi's Sarcoma-Associated Herpesvirus Infection and Replication by MEK/ERK, JNK, and p38 Multiple Mitogen-Activated Protein Kinase Pathways during Primary Infection","year":2006,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Viral-associated cancers and disorders","field":"Medicine","cited_by":129,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Texas Health Science Center at San Antonio; National Institute of Dental and Craniofacial Research; National Natural Science Foundation of China; National Cancer Institute; National Science Foundation; National Institutes of Health; School of Medicine, New York University; York University","keywords":"Biology; MAPK/ERK pathway; Lytic cycle; Infectivity; Kaposi's sarcoma-associated herpesvirus; Virology; Protein kinase A; Kinase; Gammaherpesvirinae; Cell biology; Virus; Herpesviridae","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001312907,0.0003738372,0.000215821,0.0001309823,0.0001693193,0.0002969358,0.0001875533,0.0001526638,0.0006372857],"category_scores_gemma":[0.0001088142,0.000124385,0.0002707816,0.00007575847,0.0001585724,0.0002336069,0.0001960183,0.000510775,0.000207705],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002872203,"about_ca_system_score_gemma":0.0002270317,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004274338,"about_ca_topic_score_gemma":0.0006244387,"domain_scores_codex":[0.9998461,0.00002619516,0.00001198732,0.00002068078,0.00003561975,0.00005930391],"domain_scores_gemma":[0.9999549,0.00000965752,0.000009528953,0.000004200642,0.000008838259,0.00001288359],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001224668,0.00005971695,0.0001129722,0.00005188644,0.000003630819,0.00002666421,0.00001777472,0.00005485247,0.9978054,0.00007824076,0.00003872829,0.001627514],"study_design_scores_gemma":[0.00001579431,0.000363665,0.003758432,0.000007644099,0.00001651281,0.0001775366,0.00003102508,0.00161086,0.99246,0.00006741421,0.001485424,0.00000580802],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929516,0.003124265,0.002042566,0.00005607057,0.00004294581,0.00004237663,0.0001785021,0.0000498527,0.001511761],"genre_scores_gemma":[0.9943523,0.001930645,0.002074741,0.00002861446,0.00001777138,0.00006437898,0.000248902,0.000005938054,0.001276641],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006372857,"threshold_uncertainty_score":0.002131939,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009368083388868352,"score_gpt":0.231191634659834,"score_spread":0.2218235512709656,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}