{"id":"W2139424556","doi":"10.1002/prot.21901","title":"Role of the amino acid sequence in domain swapping of the B1 domain of protein G","year":2008,"lang":"en","type":"article","venue":"Proteins Structure Function and Bioinformatics","topic":"Protein Structure and Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Hospital for Sick Children","keywords":"Dimer; Monomer; Side chain; Chemistry; Molecular dynamics; Amino acid; Sequence (biology); Stereochemistry; Protein structure; Crystallography; Computational chemistry; Biochemistry; Polymer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001328343,0.0001601014,0.0002064754,0.0000520027,0.00009975527,0.000005342183,0.0002543175,0.0001895848,0.000007042373],"category_scores_gemma":[0.00006511848,0.00009270068,0.00009450308,0.0002683406,0.0003763346,0.000014436,0.0001869926,0.0001692388,1.320758e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001370345,"about_ca_system_score_gemma":0.0001183524,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003192603,"about_ca_topic_score_gemma":0.00007939053,"domain_scores_codex":[0.9989302,0.00005910911,0.0004875918,0.0001261383,0.0002366596,0.0001602605],"domain_scores_gemma":[0.9989975,0.000004694686,0.0004551222,0.0004189756,0.00009426274,0.00002944129],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009344607,0.00001357402,0.006040793,0.0001993754,0.00002373726,1.029657e-7,0.000468873,0.00004075551,0.9899842,0.001273009,0.000006166874,0.001855926],"study_design_scores_gemma":[0.0007942038,0.0002446306,0.03442089,0.0001326815,0.00001499906,0.00005269193,0.000573209,0.0002787231,0.9514999,0.01098561,0.0008317735,0.0001706455],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953915,0.0002907112,0.002691427,0.00006414692,0.00007104294,0.0009183208,0.00007159504,0.000004233571,0.0004970579],"genre_scores_gemma":[0.9890436,0.00002291718,0.01076023,0.00006624836,0.00003032553,0.00001685898,0.00001469599,0.000008108455,0.00003704268],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03848431,"threshold_uncertainty_score":0.3780224,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005447336659594137,"score_gpt":0.1897542321590569,"score_spread":0.1843068954994628,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}