{"id":"W2139556255","doi":"10.1161/atvbaha.109.201475","title":"Simvastatin Decreases Endothelial Progenitor Cell Apoptosis in the Kidney of Hypertensive Hypercholesterolemic Pigs","year":2010,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute","keywords":"Simvastatin; Kidney; Endocrinology; Renal function; Internal medicine; Progenitor cell; Medicine; Oxidative stress; Endothelial progenitor cell; Fibrosis; Lipoprotein; Apoptosis; Pharmacology; Cholesterol; Chemistry; Biology; Stem cell; Biochemistry; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003293131,0.0002466812,0.0003583002,0.00006446425,0.0001012816,0.00002698026,0.0003129783,0.0002501189,0.00003410832],"category_scores_gemma":[0.00008652609,0.0001751857,0.0002249275,0.0001117258,0.000327033,0.00000817506,0.0001155916,0.0001434315,0.0000046999],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005030416,"about_ca_system_score_gemma":0.00006764634,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001624319,"about_ca_topic_score_gemma":0.0001132283,"domain_scores_codex":[0.998548,0.000197666,0.0003445365,0.0004704593,0.0001085991,0.0003307654],"domain_scores_gemma":[0.9991254,0.00005215662,0.0001288072,0.0004906052,0.00009298514,0.0001100482],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000007475681,0.0001463366,0.1538469,0.00002049201,0.00006177621,2.482072e-8,0.000161658,6.402338e-7,0.8450226,0.00004924549,0.0003282893,0.0003545845],"study_design_scores_gemma":[0.001472691,0.0006618263,0.7402224,0.00003829901,0.0001261186,0.000002760669,0.0005200902,0.00002001429,0.2439391,0.00003879814,0.01258272,0.000375119],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987722,0.0001555979,0.00008390669,0.0002751828,0.0002037662,0.0003019814,0.0001081821,0.000007261391,0.00009189281],"genre_scores_gemma":[0.995387,0.001974119,0.0006340778,0.0015337,0.0002218073,0.0001148572,0.0001037969,0.00002765761,0.000003001902],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6010834,"threshold_uncertainty_score":0.7143866,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01884388041979353,"score_gpt":0.2626990726098609,"score_spread":0.2438551921900673,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}