{"id":"W2139556255","doi":"10.1161/atvbaha.109.201475","title":"Simvastatin Decreases Endothelial Progenitor Cell Apoptosis in the Kidney of Hypertensive Hypercholesterolemic Pigs","year":2010,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute","keywords":"Simvastatin; Kidney; Endocrinology; Renal function; Internal medicine; Progenitor cell; Medicine; Oxidative stress; Endothelial progenitor cell; Fibrosis; Lipoprotein; Apoptosis; Pharmacology; Cholesterol; Chemistry; Biology; Stem cell; Biochemistry; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000243087,0.0002721969,0.0005156152,0.0003813908,0.0001923472,0.0002579811,0.0002130815,0.0003322813,0.000806653],"category_scores_gemma":[0.000201202,0.000190232,0.0003354489,0.0001555392,0.0002782675,0.0002592939,0.0001973088,0.0005362148,0.0001903663],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002608071,"about_ca_system_score_gemma":0.0003616599,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001315485,"about_ca_topic_score_gemma":0.001466315,"domain_scores_codex":[0.9998281,0.00003255024,0.00001661185,0.00003513383,0.00003764496,0.00004999137],"domain_scores_gemma":[0.9998066,0.00002304578,0.00006475989,0.00002091623,0.00003099342,0.00005380543],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00311106,0.0003756252,0.002254618,0.00007975676,0.0000290768,0.00008860193,0.00005383602,0.00006448879,0.9905371,0.00003692179,0.0000484401,0.003320469],"study_design_scores_gemma":[0.0005360983,0.01350285,0.08341798,0.00003251653,0.0002377152,0.0004733157,0.0002771581,0.002344246,0.8966519,0.0001220062,0.002378551,0.00002568843],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998378,0.0005470148,0.0005854729,0.00004243284,0.00001234636,0.00001409949,0.00007806163,0.00002416865,0.0003183926],"genre_scores_gemma":[0.9964129,0.0007262724,0.0007728504,0.00008676555,0.00001361594,0.00004736353,0.0002572429,0.00001293824,0.001670028],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001315485,"threshold_uncertainty_score":0.002698541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01884388041979353,"score_gpt":0.2626990726098609,"score_spread":0.2438551921900673,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}