{"id":"W2139565470","doi":"10.1016/j.rbmo.2013.03.006","title":"The ethics of creating children with three genetic parents","year":2013,"lang":"en","type":"article","venue":"Reproductive BioMedicine Online","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":151,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Legitimacy; Offspring; Egg donation; Ethical issues; Slippery slope; Assisted reproductive technology; Political science; Engineering ethics; Law and economics; Environmental ethics; Medicine; Law; Pregnancy; Sociology; Gynecology; Biology; Genetics; Infertility; Engineering; Philosophy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01898385,0.0002817492,0.0002710016,0.0003674506,0.009616253,0.006178773,0.001171724,0.009199212,0.009354074],"category_scores_gemma":[0.03957054,0.0003688155,0.0003223277,0.0003336612,0.0174037,0.003226938,0.007186834,0.009050746,0.001842884],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002700022,"about_ca_system_score_gemma":0.007308941,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001430405,"about_ca_topic_score_gemma":0.003023858,"domain_scores_codex":[0.9807085,0.01395769,0.0003893623,0.0007635211,0.002717862,0.001463095],"domain_scores_gemma":[0.9730551,0.01691426,0.001573216,0.003108318,0.001823372,0.003525644],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.00004035329,0.00009203293,0.001516469,0.00002370995,0.000006067497,0.001832334,0.01578981,0.0001881413,0.0003647037,0.9372283,0.0222916,0.02062661],"study_design_scores_gemma":[0.00005403488,0.00009075949,0.001469672,0.0003773279,0.00003451933,0.007046342,0.01860735,0.0009849648,0.002732679,0.503959,0.4645823,0.00006102842],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.09570641,0.001960916,0.02732931,0.4553853,0.002697289,0.0001439453,0.0001100888,0.0001095774,0.4165572],"genre_scores_gemma":[0.8723727,0.001116357,0.01446195,0.02927376,0.000566696,0.0002962379,0.00003812818,0.00008032106,0.08179376],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01898385,"threshold_uncertainty_score":0.1003973,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01764201705371635,"score_gpt":0.2810615870784201,"score_spread":0.2634195700247037,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}