{"id":"W2139585567","doi":"10.1186/1756-8722-6-17","title":"A double-blind, randomized, multicenter phase 2 study of prasugrel versus placebo in adult patients with sickle cell disease","year":2013,"lang":"en","type":"article","venue":"Journal of Hematology & Oncology","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital Notre-Dame","funders":"Daiichi-Sankyo; Daiichi Sankyo Europe; Eli Lilly and Company","keywords":"Prasugrel; Medicine; Placebo; Thienopyridine; Internal medicine; Clinical endpoint; P2Y12; Randomized controlled trial; Gastroenterology; Clopidogrel; Myocardial infarction; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003024795,0.002199774,0.004880547,0.0006079186,0.0006690768,0.001177551,0.0009253527,0.00222225,0.007805697],"category_scores_gemma":[0.002902637,0.00113122,0.001746665,0.0005133511,0.001544756,0.001475335,0.0004949404,0.002819581,0.001147922],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005797584,"about_ca_system_score_gemma":0.001636994,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005109549,"about_ca_topic_score_gemma":0.00103813,"domain_scores_codex":[0.9988422,0.0006119057,0.00008950095,0.0002288228,0.00009076711,0.0001368355],"domain_scores_gemma":[0.9986002,0.0003834339,0.0003516564,0.0001203545,0.0001421833,0.0004021905],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9845404,0.007551901,0.000205854,0.0003544515,0.0004037933,0.00002142557,0.00003258037,0.0001122639,0.001755559,0.00004811472,0.0003037622,0.004669959],"study_design_scores_gemma":[0.957149,0.04183327,0.0004477148,0.000009421267,0.0001311986,0.00001054968,0.000006630315,0.0001096878,0.0001027907,0.00004016772,0.0001537315,0.000005812411],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9738013,0.005323938,0.001782577,0.001020399,0.001399903,0.01343684,0.001329921,0.0002188592,0.00168622],"genre_scores_gemma":[0.9602302,0.004042066,0.004561312,0.002286862,0.001381638,0.02296497,0.001241273,0.00004615458,0.003245373],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007805697,"threshold_uncertainty_score":0.02611268,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01284671009892779,"score_gpt":0.3061343443915623,"score_spread":0.2932876342926345,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}