{"id":"W2139624089","doi":"10.1002/anie.200890251","title":"Cover Picture: Solid‐Supported Synthesis and Biological Evaluation of the Lantibiotic Peptide Bis(desmethyl) Lacticin 3147 A2 (Angew. Chem. Int. Ed. 49/2008)","year":2008,"lang":"en","type":"paratext","venue":"Angewandte Chemie International Edition","topic":"Biotin and Related Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Lantibiotics; Peptide; Cover (algebra); Desmethyl; Chemistry; Bacteria; Combinatorial chemistry; Stereochemistry; Antimicrobial; Bacteriocin; Biochemistry; Biology; Organic chemistry; Engineering; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004153351,0.0003774232,0.000387424,0.00009518231,0.0001477321,0.0000283167,0.0003298983,0.0009888359,0.0009550136],"category_scores_gemma":[0.0007431194,0.0002668842,0.000246316,0.0001174382,0.0004220162,0.00001259623,0.000243556,0.0004403053,0.00008582811],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009912117,"about_ca_system_score_gemma":0.0002118209,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003403806,"about_ca_topic_score_gemma":0.00001087852,"domain_scores_codex":[0.9979619,0.0001448921,0.0004598469,0.0005683009,0.0006192061,0.0002458283],"domain_scores_gemma":[0.9983487,0.00009711997,0.0005227574,0.0003193438,0.0006469373,0.00006510357],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001042559,0.0001224979,0.0002611426,0.00005983024,0.000708823,0.000001696316,0.00005995136,0.00002535427,0.40046,0.000003388448,0.5978842,0.000308891],"study_design_scores_gemma":[0.0005817053,0.0000675651,0.003203305,0.0002096509,0.0002658856,0.0000605673,0.00006419497,0.00003143977,0.8585849,0.00002191351,0.1366222,0.0002867045],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7050142,0.03319787,0.0004872241,0.00457372,0.01778129,0.002138687,0.003498246,0.00007291631,0.2332358],"genre_scores_gemma":[0.9552026,0.0282971,0.00005893318,0.0003504085,0.002300134,0.00004525734,0.002995013,0.00003917117,0.01071141],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.461262,"threshold_uncertainty_score":0.9999784,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02383802853432621,"score_gpt":0.2919289678420381,"score_spread":0.2680909393077119,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}