{"id":"W2139795441","doi":"10.1074/jbc.m204923200","title":"Protein Kinase A Site-specific Phosphorylation Regulates ATP-binding Cassette A1 (ABCA1)-mediated Phospholipid Efflux","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":128,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Children's Hospital; Xenon Pharmaceuticals (Canada); Children's & Women's Health Centre of British Columbia","funders":"","keywords":"ABCA1; Efflux; Phosphorylation; Phospholipid; Chemistry; Biochemistry; Cell biology; Kinase; Protein kinase A; Biology; Membrane; Gene; Transporter","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008915673,0.0002473795,0.000146635,0.0001357748,0.000181644,0.0002663682,0.0001397308,0.0002494971,0.001017878],"category_scores_gemma":[0.0001281429,0.000153776,0.0001548567,0.00009315464,0.0002516909,0.0002066712,0.0001607906,0.0003104559,0.0003917259],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003243857,"about_ca_system_score_gemma":0.0001761811,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004501855,"about_ca_topic_score_gemma":0.0005149762,"domain_scores_codex":[0.999931,0.00001737135,0.000005676799,0.00001534886,0.00001163551,0.00001893561],"domain_scores_gemma":[0.9999545,0.000008172296,0.00001833963,0.000004086123,0.000004962485,0.000009870361],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001636043,0.00002303131,0.0003111938,0.00002850517,0.000003765301,0.00007637084,0.000007567372,0.0001006636,0.9977666,0.0001797321,0.0000547383,0.001284272],"study_design_scores_gemma":[0.00006779004,0.0002035355,0.01206619,0.000006489947,0.0000243198,0.0006924944,0.00003349229,0.002399478,0.9814798,0.0003205773,0.002697109,0.000008681709],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954136,0.001922512,0.001273911,0.0001829512,0.00003507243,0.00001300909,0.00009833503,0.00003161166,0.001029071],"genre_scores_gemma":[0.9963318,0.001381981,0.00103125,0.00003963076,0.00001322155,0.0000155389,0.000114501,0.000007317298,0.001064808],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001017878,"threshold_uncertainty_score":0.003405094,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03121698131423451,"score_gpt":0.2406936407291,"score_spread":0.2094766594148655,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}