{"id":"W2139840449","doi":"10.1074/mcp.r400009-mcp200","title":"Interaction Networks of the Molecular Machines That Decode, Replicate, and Maintain the Integrity of the Human Genome","year":2004,"lang":"en","type":"review","venue":"Molecular & Cellular Proteomics","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Genome Canada","keywords":"Biology; DNA replication; Computational biology; Genome; Genetics; Gene; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006640678,0.0005971367,0.0008633097,0.00005619257,0.0002388784,0.00006253558,0.001556972,0.0006398362,0.000004522722],"category_scores_gemma":[0.00008327285,0.0003395801,0.001011645,0.0002595449,0.0004776865,0.000004647558,0.001318624,0.000941066,7.183285e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001039866,"about_ca_system_score_gemma":0.0002736238,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000103906,"about_ca_topic_score_gemma":0.00003775014,"domain_scores_codex":[0.9972607,0.0005625277,0.0008562204,0.0006814079,0.0002784648,0.000360718],"domain_scores_gemma":[0.9963038,0.00002222772,0.00128516,0.002199649,0.0001223886,0.00006676315],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004422539,0.0003187822,0.0001610837,0.009578072,0.001601962,0.00002233612,0.0001206012,0.006104791,0.9395197,0.0133958,0.00002450837,0.02910815],"study_design_scores_gemma":[0.001706055,0.0005507816,0.0004072499,0.009080723,0.003977722,0.0006799302,0.0001718388,0.002640631,0.8070011,0.009944954,0.1611113,0.002727719],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.2194207,0.7603459,0.0167584,0.00009332946,0.0002391039,0.002911985,0.00009195355,0.000009509423,0.0001290581],"genre_scores_gemma":[0.3557088,0.6412047,0.001718234,0.0001755142,0.0001334247,0.0002942465,0.0003892988,0.0002455645,0.0001302007],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.1610868,"threshold_uncertainty_score":0.9999056,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01362701321091124,"score_gpt":0.2623514826338408,"score_spread":0.2487244694229296,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}