{"id":"W2139949759","doi":"10.4161/rdis.24883","title":"IGSF1 deficiency syndrome","year":2013,"lang":"en","type":"article","venue":"Rare Diseases","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Ipsen","keywords":"Internal medicine; Endocrinology; Medicine; Central hypothyroidism; Prolactin; Delayed puberty; Paracrine signalling; Growth hormone deficiency; Hormone; Growth hormone; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00002078656,0.0001644617,0.0002446135,0.0001103997,0.00008695784,0.00003687235,0.000108044,0.0000635402,0.002147716],"category_scores_gemma":[0.0001488788,0.00012889,0.0001519764,0.0002365047,0.00006532276,0.0002367214,0.00004128334,0.0001002924,0.002067813],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003565809,"about_ca_system_score_gemma":0.00009556738,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008207392,"about_ca_topic_score_gemma":4.484961e-7,"domain_scores_codex":[0.9989055,0.00001784941,0.0002119263,0.0002552426,0.0002795485,0.0003298855],"domain_scores_gemma":[0.9990614,0.00004089714,0.00004249785,0.0003415982,0.0001054451,0.0004081675],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00008872297,0.001237239,0.871886,0.0004238049,0.000103902,0.0007842248,0.0002575384,0.000001518681,0.002183581,0.0009791001,0.1054441,0.01661026],"study_design_scores_gemma":[0.0005916376,0.0002647595,0.9949139,0.00005585172,0.000114841,0.0001812786,0.0001819101,0.00003112797,0.0002485407,0.0004816702,0.002754675,0.0001798103],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896708,0.002547055,0.00001955577,0.0005684051,0.0001471818,0.0003990791,0.00004164525,0.000195383,0.006410924],"genre_scores_gemma":[0.9975266,0.00004395423,0.00007618999,0.0009773707,0.00007431243,0.00006465636,0.0001054094,0.00002543648,0.001106088],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1230279,"threshold_uncertainty_score":0.9987645,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00990408306758912,"score_gpt":0.2280215703399776,"score_spread":0.2181174872723885,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}