{"id":"W2139949759","doi":"10.4161/rdis.24883","title":"IGSF1 deficiency syndrome","year":2013,"lang":"en","type":"article","venue":"Rare Diseases","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Ipsen","keywords":"Internal medicine; Endocrinology; Medicine; Central hypothyroidism; Prolactin; Delayed puberty; Paracrine signalling; Growth hormone deficiency; Hormone; Growth hormone; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001090275,0.001317021,0.0003768325,0.0008170977,0.0006926047,0.0003432989,0.0004272637,0.0008912354,0.005882133],"category_scores_gemma":[0.00076659,0.0001044621,0.0003225893,0.000762579,0.0005227298,0.0002120996,0.0004444263,0.0005090541,0.0007989895],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004442658,"about_ca_system_score_gemma":0.0003395476,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002288016,"about_ca_topic_score_gemma":0.001420347,"domain_scores_codex":[0.9998293,0.00001716267,0.00001137165,0.00005339332,0.00004095104,0.00004775792],"domain_scores_gemma":[0.9998085,0.00005450918,0.0000382772,0.000008529102,0.00002541993,0.00006481687],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.0009811799,0.0001071757,0.1118485,0.0007661671,0.0002378086,0.6451674,0.001302386,0.0009226319,0.07815437,0.008175056,0.01843285,0.1339044],"study_design_scores_gemma":[0.00007505043,0.0002287817,0.05759224,0.0002384806,0.0001535623,0.8921304,0.0002926405,0.0006529651,0.008388729,0.0015441,0.03867453,0.00002843816],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9296147,0.01314059,0.004671107,0.002689557,0.0005488954,0.00009867989,0.001799034,0.0007124891,0.0467249],"genre_scores_gemma":[0.9872336,0.002697351,0.001532924,0.0006111866,0.0001408926,0.00002027717,0.0007675769,0.00003567552,0.006960468],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005882133,"threshold_uncertainty_score":0.01967776,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00990408306758912,"score_gpt":0.2280215703399776,"score_spread":0.2181174872723885,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}