{"id":"W2140081746","doi":"10.2119/molmed.2010.00214","title":"S1P Is Associated with Protection in Human and Experimental Cerebral Malaria","year":2011,"lang":"en","type":"article","venue":"Molecular Medicine","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"Occupational Cancer Research Centre; Toronto General Hospital; Centre for Global Health Research; University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research","keywords":"Plasmodium berghei; Cerebral Malaria; Sphingosine-1-phosphate; Inflammation; Endothelial activation; Sphingosine; Immunology; Evans Blue; Endothelial stem cell; Sphingolipid; Biology; Pharmacology; Medicine; Cancer research; Cell biology; Malaria; Plasmodium falciparum; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001228415,0.0003415852,0.0003332724,0.0002368325,0.0001373189,0.0001683884,0.0001229135,0.0002532694,0.002343021],"category_scores_gemma":[0.0001872478,0.0001119834,0.00015223,0.000176186,0.0002740852,0.00009642958,0.0001533252,0.0004176859,0.0002431239],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002180698,"about_ca_system_score_gemma":0.0001884936,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007095879,"about_ca_topic_score_gemma":0.000636959,"domain_scores_codex":[0.9999356,0.00001646339,0.000004205595,0.00001223878,0.00001127549,0.00002019394],"domain_scores_gemma":[0.9998989,0.000008395627,0.00004366423,0.000007187862,0.00001004618,0.00003181518],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005746938,0.0002520758,0.002142234,0.0003032217,0.00005003942,0.0005370926,0.00008433969,0.0001306737,0.9754156,0.0002843396,0.0008286406,0.01422484],"study_design_scores_gemma":[0.000441764,0.01117244,0.1444842,0.00009854276,0.0001857291,0.004995608,0.0001859982,0.00154848,0.8198643,0.0004341993,0.01655776,0.0000309295],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929396,0.004278949,0.0008123805,0.0001808474,0.00003450073,0.00003572813,0.0005481049,0.0001007482,0.001069257],"genre_scores_gemma":[0.9964205,0.00139588,0.0004157651,0.00005203538,0.00001573484,0.00004477238,0.0005317699,0.00001118724,0.001112396],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002343021,"threshold_uncertainty_score":0.00783819,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01699218141347817,"score_gpt":0.2419407802715664,"score_spread":0.2249485988580883,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}