{"id":"W2140088680","doi":"10.1021/bi0010625","title":"Detailed Structural Analysis of Glycosidase/Inhibitor Interactions:  Complexes of Cex from <i>Cellulomonas fimi</i> with Xylobiose-Derived Aza-Sugars<sup>,</sup>","year":2000,"lang":"en","type":"article","venue":"Biochemistry","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University of British Columbia","funders":"Killam Trusts","keywords":"Chemistry; Xylobiose; Stereochemistry; Glycoside hydrolase; Nucleophile; Bacillus circulans; Hydrogen bond; Binding site; Glycosidic bond; Xylanase; Molecule; Crystallography; Enzyme; Catalysis; Organic chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00006697184,0.000531604,0.001018151,0.00008581778,0.0001168595,0.00005008675,0.0005522554,0.0003158732,0.01838001],"category_scores_gemma":[0.00007110168,0.0004944942,0.0006032827,0.0006561453,0.000414216,0.0001173319,0.00008171154,0.000312452,0.00001255955],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001255945,"about_ca_system_score_gemma":0.0001156703,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002743925,"about_ca_topic_score_gemma":0.00003634175,"domain_scores_codex":[0.9973879,0.00003231103,0.0009134553,0.0007723659,0.0004815532,0.0004123774],"domain_scores_gemma":[0.997606,0.000337739,0.0004826715,0.001149968,0.0002031397,0.0002204785],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000612866,0.0001837734,0.004402502,0.0002969319,0.002020566,0.00002112649,0.0002983948,0.00051028,0.9905878,0.000001159194,0.0002036716,0.0008609809],"study_design_scores_gemma":[0.0008762246,0.00001805392,0.0004252487,0.0002432967,0.001638765,0.00001314525,0.0009939685,0.00381889,0.9912527,0.00002061718,0.0001882642,0.0005107928],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910487,0.0003880382,0.000007141683,0.00004087727,0.00002029067,0.00007298005,0.001952749,0.0001021717,0.006367039],"genre_scores_gemma":[0.9964169,0.00003643019,0.0005922028,0.00002508099,0.0002114109,0.00002615245,0.001405403,0.00005048131,0.001235915],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01836745,"threshold_uncertainty_score":0.9997507,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008718123689571452,"score_gpt":0.2150812636177547,"score_spread":0.2063631399281832,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}