{"id":"W2140111803","doi":"10.1152/ajpregu.00644.2011","title":"UPEI-100, a conjugate of lipoic acid and apocynin, mediates neuroprotection in a rat model of ischemia/reperfusion","year":2012,"lang":"en","type":"article","venue":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","topic":"Biochemical Acid Research Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Prince Edward Island","funders":"University of Prince Edward Island; Atlantic Canada Opportunities Agency","keywords":"Apocynin; Neuroprotection; Lipoic acid; Conjugate; Pharmacology; Ischemia; Chemistry; Medicine; Antioxidant; Oxidative stress; Biochemistry; Internal medicine; NADPH oxidase; Mathematics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002719303,0.0009524589,0.0006643523,0.0005608529,0.0001533539,0.0002859358,0.0003153383,0.0004909002,0.001179551],"category_scores_gemma":[0.0001432237,0.0002279074,0.0003053443,0.0002952469,0.000472421,0.0004411341,0.0002601954,0.001172923,0.0002704552],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002272409,"about_ca_system_score_gemma":0.0003325446,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00024717,"about_ca_topic_score_gemma":0.0004442241,"domain_scores_codex":[0.999867,0.00002053362,0.00001624705,0.00002695559,0.0000282161,0.00004106808],"domain_scores_gemma":[0.9998419,0.00001486167,0.00005311922,0.00001601394,0.00001572743,0.00005831931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006072644,0.0002597432,0.00008994618,0.00006156177,0.00001499285,0.00005716766,0.00001087155,0.00005660119,0.9970884,0.00006371477,0.00002354972,0.001666344],"study_design_scores_gemma":[0.00005125666,0.002573886,0.0011524,0.000007368282,0.00003037865,0.00008548152,0.00001114037,0.0003310631,0.9953561,0.00002586009,0.0003711999,0.00000394585],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929756,0.001777299,0.004096965,0.00008968295,0.00004368652,0.00006800186,0.0001093456,0.000128203,0.0007112102],"genre_scores_gemma":[0.9900737,0.00241854,0.004507864,0.00006424316,0.00003119203,0.0001091786,0.0004415765,0.000022548,0.002331297],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001179551,"threshold_uncertainty_score":0.003945947,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02157009196400446,"score_gpt":0.2862589779076409,"score_spread":0.2646888859436364,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}