{"id":"W2140111803","doi":"10.1152/ajpregu.00644.2011","title":"UPEI-100, a conjugate of lipoic acid and apocynin, mediates neuroprotection in a rat model of ischemia/reperfusion","year":2012,"lang":"en","type":"article","venue":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","topic":"Biochemical Acid Research Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Prince Edward Island","funders":"University of Prince Edward Island; Atlantic Canada Opportunities Agency","keywords":"Apocynin; Neuroprotection; Lipoic acid; Conjugate; Pharmacology; Ischemia; Chemistry; Medicine; Antioxidant; Oxidative stress; Biochemistry; Internal medicine; NADPH oxidase; Mathematics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000302706,0.000299528,0.001031029,0.0001503425,0.00005599931,0.000003331525,0.0001930544,0.0001512435,0.000009960627],"category_scores_gemma":[0.0001548239,0.0002073217,0.0001460971,0.0002046683,0.00267411,0.0000305307,0.0002291719,0.0004827096,5.447197e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001961725,"about_ca_system_score_gemma":0.00008495471,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003504276,"about_ca_topic_score_gemma":0.00001048889,"domain_scores_codex":[0.998138,0.0004623519,0.0005942106,0.0003225018,0.0001490929,0.0003338054],"domain_scores_gemma":[0.9983238,0.0001177968,0.0007780773,0.0002003612,0.0004452128,0.0001347504],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001613322,0.0002209367,0.001364621,0.00004136983,0.0001766189,1.997062e-7,0.001043435,0.0001153121,0.9945355,0.0001549338,0.000195874,0.0005378948],"study_design_scores_gemma":[0.0007602996,0.00326451,0.01643856,0.00006784167,0.00003232454,0.0000150156,0.001850557,0.0004443149,0.9764404,0.0004394684,0.00006857522,0.0001781787],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959459,0.003504641,0.0001411846,0.00009467283,0.00006630031,0.0001819601,0.00001724016,0.000002693041,0.00004545911],"genre_scores_gemma":[0.9978334,0.00115972,0.0007287712,0.00009364977,0.0001261352,0.00002071272,0.00001166746,0.00001152506,0.00001438864],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01809513,"threshold_uncertainty_score":0.9852868,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02157009196400446,"score_gpt":0.2862589779076409,"score_spread":0.2646888859436364,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}