{"id":"W2140114578","doi":"10.1158/1940-6207.capr-09-0194","title":"Vaccine against MUC1 Antigen Expressed in Inflammatory Bowel Disease and Cancer Lessens Colonic Inflammation and Prevents Progression to Colitis-Associated Colon Cancer","year":2010,"lang":"en","type":"article","venue":"Cancer Prevention Research","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":82,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Cancer Institute; U.S. Public Health Service","keywords":"Immunology; Medicine; Inflammation; Inflammatory bowel disease; Cancer; Acquired immune system; Antigen; Immune system; Colorectal cancer; CTL*; Immunity; Colitis; Cancer research; Disease; CD8; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001259071,0.0002465105,0.0002934621,0.0002303393,0.00007227054,0.0001602586,0.0001691535,0.0003714072,0.0009640909],"category_scores_gemma":[0.0001805086,0.00009874831,0.0001717798,0.00009903291,0.0001971691,0.0001823936,0.0001070065,0.0005754878,0.0001829145],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001679732,"about_ca_system_score_gemma":0.0002737436,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003228668,"about_ca_topic_score_gemma":0.0004938269,"domain_scores_codex":[0.9999213,0.00001535513,0.000006294415,0.00001373597,0.00001530381,0.00002795767],"domain_scores_gemma":[0.9999015,0.00001183893,0.00003666516,0.000009676761,0.000008436761,0.00003180613],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001406649,0.000640192,0.0007043871,0.0001751437,0.00001697416,0.0000741608,0.00002085161,0.0003132684,0.9794831,0.0002756617,0.0002699276,0.01661965],"study_design_scores_gemma":[0.00120972,0.02931132,0.03754544,0.0000930581,0.0001971636,0.001345786,0.00006966858,0.003379066,0.9066218,0.0004108256,0.01979417,0.00002199033],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931582,0.004226498,0.00127476,0.0002508508,0.00008968927,0.00003877389,0.00006118786,0.0001082584,0.0007918429],"genre_scores_gemma":[0.9946858,0.002208825,0.001329995,0.00009861874,0.00004016203,0.00003654159,0.0001540742,0.00001188607,0.001434001],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009640909,"threshold_uncertainty_score":0.003225267,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02424996115375696,"score_gpt":0.3701940916865953,"score_spread":0.3459441305328383,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}