{"id":"W2140137267","doi":"10.2174/156652306775515510","title":"Synthetic and Natural Polycations for Gene Therapy: State of the Art and New Perspectives","year":2006,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"Animal Genetics and Reproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":89,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital du Sacré-Cœur de Montréal","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Arthritis Society","keywords":"Genetic enhancement; Natural (archaeology); Computational biology; Medicine; Gene; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008226443,0.0009992118,0.001097128,0.001567138,0.0002762754,0.0009571512,0.0008139652,0.001271965,0.003232419],"category_scores_gemma":[0.0003315184,0.0003762128,0.0004002975,0.001407091,0.0006642919,0.001776514,0.0004359469,0.001376824,0.001970699],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006360078,"about_ca_system_score_gemma":0.0007167906,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005692043,"about_ca_topic_score_gemma":0.001042824,"domain_scores_codex":[0.9997556,0.00003965792,0.00002657114,0.00004062348,0.0001178093,0.00001979819],"domain_scores_gemma":[0.9997632,0.000116717,0.00003114027,0.00001025397,0.00005680241,0.00002192952],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001202848,0.0002128315,0.0001939754,0.01374224,0.00005828993,0.0006160907,0.000145748,0.001076387,0.03328848,0.0113228,0.01129883,0.927924],"study_design_scores_gemma":[0.0000318682,0.0002567194,0.0004891646,0.001295319,0.00004672516,0.002087329,0.00008433588,0.0003407338,0.008548897,0.003565051,0.983224,0.00002989053],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005266399,0.9962431,0.0009023274,0.0002366832,0.000217987,0.000008985968,0.000009181256,0.00001124296,0.001843718],"genre_scores_gemma":[0.001845867,0.9957972,0.0009853855,0.0001279182,0.0001436185,0.00001321087,0.00001642311,0.000002388517,0.001068002],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003232419,"threshold_uncertainty_score":0.01081353,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04386803663991975,"score_gpt":0.3323648828359524,"score_spread":0.2884968461960327,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}