{"id":"W2140137267","doi":"10.2174/156652306775515510","title":"Synthetic and Natural Polycations for Gene Therapy: State of the Art and New Perspectives","year":2006,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"Animal Genetics and Reproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":89,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital du Sacré-Cœur de Montréal","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Arthritis Society","keywords":"Genetic enhancement; Natural (archaeology); Computational biology; Medicine; Gene; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001092679,0.0002734642,0.0003945777,0.00004500989,0.0001060624,0.00002446305,0.0001608462,0.00009667512,0.000002075429],"category_scores_gemma":[0.00001277673,0.0001704156,0.0002431157,0.00008257957,0.0001653025,0.000002124341,0.00005758038,0.0001067377,5.144219e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001112022,"about_ca_system_score_gemma":0.0001752477,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005459887,"about_ca_topic_score_gemma":0.000003311947,"domain_scores_codex":[0.9989136,0.00006897109,0.0002615126,0.0005056048,0.00008702427,0.0001632395],"domain_scores_gemma":[0.999219,0.00001297092,0.000236007,0.0004022928,0.00008503637,0.00004470554],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003512507,0.00006442583,0.000007450104,0.0002403644,0.0001453034,2.884913e-8,0.00007284617,0.000001862828,0.02006892,0.00001853006,0.0009367213,0.9784084],"study_design_scores_gemma":[0.0003241675,0.0001971436,0.0001535012,0.0001717217,0.00008477052,0.00001843417,0.000009832303,0.000003239546,0.01145134,0.0001020143,0.9872628,0.0002210741],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01252783,0.9856626,0.0003011436,0.00007022939,0.0003977907,0.0009408528,0.00008538402,0.000005271937,0.000008904995],"genre_scores_gemma":[0.00165806,0.9961147,0.0002095242,0.000009297625,0.0005507258,0.00005758656,0.0001327642,0.00004167007,0.001225612],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.986326,"threshold_uncertainty_score":0.6949347,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04386803663991975,"score_gpt":0.3323648828359524,"score_spread":0.2884968461960327,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}