{"id":"W2140193569","doi":"10.1128/jvi.02520-10","title":"Influence of Gag-Protease-Mediated Replication Capacity on Disease Progression in Individuals Recently Infected with HIV-1 Subtype C","year":2011,"lang":"en","type":"article","venue":"Journal of Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"AIDS Vancouver; Simon Fraser University","funders":"National Institutes of Health; Canadian Institutes of Health Research; Ragon Institute of MGH, MIT and Harvard; Harvard University; National Research Foundation; Massachusetts Institute of Technology; Massachusetts General Hospital; National Institute of Allergy and Infectious Diseases; Bill and Melinda Gates Foundation","keywords":"Biology; Viral load; Viral replication; Allele; Virology; Human leukocyte antigen; Immunology; Lentivirus; Epitope; Immune system; Genetics; Viral disease; Antibody; Virus; Gene; Antigen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003273789,0.0001814008,0.0001706165,0.0002626211,0.0002012166,0.0003725153,0.0001029901,0.0002548052,0.0006527241],"category_scores_gemma":[0.001654609,0.0001145557,0.0001657689,0.0001607463,0.0001600291,0.0001959243,0.0001567584,0.0003482289,0.0001090962],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001629195,"about_ca_system_score_gemma":0.0001514717,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001663029,"about_ca_topic_score_gemma":0.001518486,"domain_scores_codex":[0.9998228,0.00006207472,0.0000119825,0.00004170195,0.00002389597,0.00003753671],"domain_scores_gemma":[0.9991621,0.0003541906,0.0001920143,0.00006157131,0.00005387617,0.0001763549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001965141,0.0001460609,0.9648703,0.00001532322,0.00008077299,0.0002334811,0.0002231158,0.0004036495,0.0238688,0.00005154382,0.00007297663,0.008068822],"study_design_scores_gemma":[0.00001205109,0.0007343767,0.9963575,0.000003917635,0.00002564405,0.0004096027,0.00008462671,0.0007148667,0.001513224,0.00003967607,0.00009808016,0.000006379043],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9997807,0.00005714523,0.00001842238,0.000005248976,6.98891e-7,0.000001283015,0.00002107173,0.000001051847,0.0001144214],"genre_scores_gemma":[0.9998633,0.000016315,0.00002348079,0.000004134066,0.000001402727,0.000001002495,0.00003193122,7.306404e-7,0.00005764566],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001663029,"threshold_uncertainty_score":0.003306687,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02505923208281981,"score_gpt":0.2759403772597724,"score_spread":0.2508811451769526,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}