{"id":"W2140202225","doi":"10.1128/aac.49.5.1988-1993.2005","title":"Role of the ABC Transporter MRPA (PGPA) in Antimony Resistance in <i>Leishmania infantum</i> Axenic and Intracellular Amastigotes","year":2005,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":144,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier de l'Université Laval","funders":"","keywords":"Leishmania infantum; Axenic; Amastigote; Intracellular; Microbiology; Leishmania; ATP-binding cassette transporter; Transporter; Kinetoplastida; Drug resistance; Biology; Chemistry; Leishmaniasis; Biochemistry; Bacteria; Gene; Parasite hosting; Immunology; Visceral leishmaniasis; Protozoal disease; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009120976,0.0001661807,0.0001641898,0.0001790539,0.000162084,0.0003306596,0.00008811132,0.0002560745,0.0007519274],"category_scores_gemma":[0.0001113528,0.00009850632,0.0001274544,0.0001274347,0.0001478083,0.0001719369,0.0001071263,0.0001929599,0.0002367537],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001778179,"about_ca_system_score_gemma":0.0001020246,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004311673,"about_ca_topic_score_gemma":0.0004200471,"domain_scores_codex":[0.9999235,0.00001906933,0.00000522887,0.00001728702,0.0000180503,0.00001693319],"domain_scores_gemma":[0.9999444,0.00001460284,0.00001387027,0.000004803249,0.00001116275,0.00001105029],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005369476,0.000005743861,0.0002989967,0.00001455612,0.000001523848,0.00002984285,0.0000121154,0.00001370808,0.9988583,0.00005135913,0.00001276859,0.0006473017],"study_design_scores_gemma":[0.00001599606,0.0004014598,0.02679348,0.000009043145,0.0000295534,0.000586366,0.0001033637,0.0007778307,0.9678155,0.0001108904,0.003350826,0.000005562359],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979862,0.0007779082,0.0005273147,0.00008078608,0.000003378452,0.00000531348,0.0001153526,0.00001467992,0.0004890815],"genre_scores_gemma":[0.9966754,0.0006468031,0.001072619,0.000036234,0.000004769326,0.000009550436,0.0003720945,0.000006129897,0.001176399],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007519274,"threshold_uncertainty_score":0.002515376,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007622320818164109,"score_gpt":0.2374960436675053,"score_spread":0.2298737228493412,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}