{"id":"W2140261915","doi":"10.1093/glycob/cwn106","title":"Induction of HIV-1 resistance: cell susceptibility to infection is an inverse function of globotriaosyl ceramide levels","year":2008,"lang":"en","type":"article","venue":"Glycobiology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Hospital for Sick Children; Canadian Blood Services; University of Toronto","funders":"Canadian Institutes of Health Research; Ontario HIV Treatment Network","keywords":"Globotriaosylceramide; Glycosphingolipid; Cell culture; Chemistry; Population; Transfection; Cell; Molecular biology; Human immunodeficiency virus (HIV); Biology; Virology; Biochemistry; Fabry disease; Medicine; Disease; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001249749,0.0002768008,0.0002759279,0.0001541639,0.0001022252,0.0003593909,0.000155116,0.0003718274,0.001734467],"category_scores_gemma":[0.0001855595,0.0001533485,0.000170074,0.0001435838,0.0001737511,0.0002079081,0.0002472765,0.0006410565,0.0005876379],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001747638,"about_ca_system_score_gemma":0.0001006837,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002731674,"about_ca_topic_score_gemma":0.0002574592,"domain_scores_codex":[0.9998153,0.00004151169,0.00001986437,0.00002664401,0.0000434228,0.00005333913],"domain_scores_gemma":[0.9998317,0.00004389044,0.00003904523,0.00002192454,0.00002166378,0.00004171166],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007059468,0.00001533096,0.0001121235,0.00001162967,0.000001986813,0.00001357362,0.00000899671,0.00001420705,0.999201,0.00001432946,0.00001175834,0.0005243513],"study_design_scores_gemma":[0.00001507676,0.0004043915,0.007793773,0.000006881972,0.00001053815,0.0002374167,0.00003495517,0.0003114707,0.9902801,0.00002981779,0.0008709906,0.000004594699],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954008,0.002305902,0.0007908324,0.00009184264,0.00001225212,0.00002798012,0.0002494167,0.00005520666,0.001065693],"genre_scores_gemma":[0.9962842,0.0008961551,0.0008665327,0.00006461587,0.000009214959,0.00004099529,0.0003279606,0.00001357446,0.001496746],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001734467,"threshold_uncertainty_score":0.005802393,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04292986535596822,"score_gpt":0.2752883779812003,"score_spread":0.232358512625232,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}