{"id":"W2140267850","doi":"10.1186/1745-6215-12-56","title":"Randomized clinical trial comparing percutaneous closure of patent foramen ovale (PFO) using the Amplatzer PFO Occluder with medical treatment in patients with cryptogenic embolism (PC-Trial): rationale and design","year":2011,"lang":"en","type":"article","venue":"Trials","topic":"Cardiovascular and Diving-Related Complications","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Heart Institute","funders":"","keywords":"Medicine; Patent foramen ovale; Randomized controlled trial; Randomization; Warfarin; Stroke (engine); Percutaneous; Surgery; Clinical trial; Embolism; Internal medicine; Atrial fibrillation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01493325,0.004102894,0.00836359,0.0009427799,0.001243413,0.002261328,0.001745008,0.005159151,0.01330077],"category_scores_gemma":[0.01719928,0.001195424,0.003905532,0.001380482,0.0026498,0.002168298,0.001347346,0.00357129,0.002606013],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001147361,"about_ca_system_score_gemma":0.003570465,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006581477,"about_ca_topic_score_gemma":0.001033788,"domain_scores_codex":[0.9859031,0.01047786,0.0009695452,0.001301211,0.0006535867,0.0006947866],"domain_scores_gemma":[0.9930011,0.002818676,0.0015603,0.0006576898,0.0008582969,0.001103959],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9830246,0.002500663,0.001020615,0.003047159,0.0022849,0.00006793287,0.00005326801,0.0003731483,0.0005404943,0.000762357,0.001077136,0.005247704],"study_design_scores_gemma":[0.9779491,0.01689163,0.0004414623,0.0001393585,0.00154109,0.00003266388,0.00001754256,0.0004863647,0.0001416461,0.0006903364,0.001649126,0.0000196434],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.3440903,0.02384818,0.01055418,0.009287198,0.01002238,0.5836342,0.0078828,0.000489693,0.01019115],"genre_scores_gemma":[0.3696578,0.006306093,0.01795065,0.00672395,0.003531234,0.584305,0.003119781,0.00006608023,0.008339346],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.01493325,"threshold_uncertainty_score":0.0789755,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3554787166545533,"score_gpt":0.385709768071211,"score_spread":0.03023105141665766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}