{"id":"W2140293594","doi":"10.1093/mutage/get031","title":"Hepatic genotoxicity and toxicogenomic responses in Muta™Mouse males treated with dibenz[a,h]anthracene","year":2013,"lang":"en","type":"article","venue":"Mutagenesis","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada","funders":"Health Canada; Cancer Research UK; U.S. Environmental Protection Agency","keywords":"Aryl hydrocarbon receptor; Carcinogen; Genotoxicity; Benzo(a)pyrene; Anthracene; Luciferase; Gene expression; Fold change; Molecular biology; Carcinogenesis; Biology; Chemistry; Pyrene; Biochemistry; Gene; Toxicity; Transfection; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000158578,0.0002778202,0.0002753048,0.0001210632,0.000110017,0.00007027879,0.0001472601,0.0001530389,0.000119142],"category_scores_gemma":[0.00002866507,0.0002375971,0.00006405789,0.000151172,0.0001322646,0.00001022922,0.0001263242,0.00007274777,0.00002170565],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005236283,"about_ca_system_score_gemma":0.00007045684,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000976181,"about_ca_topic_score_gemma":0.001275023,"domain_scores_codex":[0.9985254,0.0001340543,0.0002639734,0.000539925,0.0001446737,0.0003919647],"domain_scores_gemma":[0.9992583,0.00003041219,0.00008000575,0.0004280782,0.00006065536,0.0001425823],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001928096,0.0001102913,0.1455572,0.00002568819,0.00005460438,0.00002324307,0.00006117734,0.00005824877,0.8517898,0.000005339144,0.00005029031,0.002071244],"study_design_scores_gemma":[0.0007075941,0.0003816298,0.3040432,0.00001228318,0.00002803094,0.0000334484,0.0001820802,0.0001439868,0.6937835,0.000009459438,0.0003736424,0.0003011394],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979244,0.0009012814,0.0002194558,0.0001255106,0.00001911223,0.0006000429,0.00005818286,0.00002275257,0.0001292181],"genre_scores_gemma":[0.9970451,0.0003963419,0.001009574,0.0001794994,0.00005675718,0.0001601615,0.00005536488,0.00004565587,0.001051543],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1584859,"threshold_uncertainty_score":0.9688927,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009207405867063994,"score_gpt":0.22936849813017,"score_spread":0.220161092263106,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}