{"id":"W2140293594","doi":"10.1093/mutage/get031","title":"Hepatic genotoxicity and toxicogenomic responses in Muta™Mouse males treated with dibenz[a,h]anthracene","year":2013,"lang":"en","type":"article","venue":"Mutagenesis","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada","funders":"Health Canada; Cancer Research UK; U.S. Environmental Protection Agency","keywords":"Aryl hydrocarbon receptor; Carcinogen; Genotoxicity; Benzo(a)pyrene; Anthracene; Luciferase; Gene expression; Fold change; Molecular biology; Carcinogenesis; Biology; Chemistry; Pyrene; Biochemistry; Gene; Toxicity; Transfection; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001004198,0.0003658325,0.0003655271,0.0006743608,0.0002244506,0.0002404342,0.0001058772,0.0002893881,0.001763548],"category_scores_gemma":[0.00008189121,0.0002476729,0.0003667568,0.0002987301,0.00024694,0.0001271904,0.0001510208,0.0004805468,0.0003952101],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002364496,"about_ca_system_score_gemma":0.0001725989,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001166717,"about_ca_topic_score_gemma":0.001765307,"domain_scores_codex":[0.9998261,0.00002088291,0.000009244088,0.0000559453,0.00004154521,0.00004615445],"domain_scores_gemma":[0.999873,0.00001182274,0.00003596694,0.00001185683,0.0000229513,0.0000442088],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005615962,0.00006113328,0.001628359,0.00001379217,0.000009504075,0.00004322787,0.00002515832,0.00003194376,0.9967823,0.00001378055,0.00002273237,0.0008064797],"study_design_scores_gemma":[0.00002831704,0.003246999,0.09230319,0.000006533927,0.00008165201,0.0002555043,0.0001691934,0.0003513486,0.9024388,0.0000436948,0.001061015,0.00001387252],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974486,0.0006996018,0.0005781739,0.00005280698,0.00002367476,0.00001600319,0.0006439888,0.00003782982,0.0004992477],"genre_scores_gemma":[0.9915431,0.0008716429,0.000832207,0.00008113323,0.00001672268,0.00005861177,0.001256788,0.00001835151,0.005321527],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001763548,"threshold_uncertainty_score":0.005899668,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009207405867063994,"score_gpt":0.22936849813017,"score_spread":0.220161092263106,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}