{"id":"W2140375010","doi":"10.1038/sj.bjp.0707451","title":"Mechanisms underlying the anti‐inflammatory activity and gastric safety of acemetacin","year":2007,"lang":"en","type":"article","venue":"British Journal of Pharmacology","topic":"Inflammatory mediators and NSAID effects","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Fondation pour la Recherche Médicale","keywords":"Chemistry; Pharmacology; Biotransformation; Indometacin; Thromboxane; Eicosanoid; Prostaglandin; Oral administration; Enzyme inhibitor; Biochemistry; Internal medicine; Arachidonic acid; Medicine; In vitro; Enzyme; Platelet","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0028014,0.0001156438,0.0004547847,0.000165966,0.0001184022,0.0000100456,0.0001077829,0.0001067062,0.0001298936],"category_scores_gemma":[0.0001250209,0.00009675165,0.0001286809,0.0001650627,0.0001684942,0.00012393,0.00004461315,0.0005653113,0.000001911628],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006149081,"about_ca_system_score_gemma":0.0001663071,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001454368,"about_ca_topic_score_gemma":0.00001222208,"domain_scores_codex":[0.9985877,0.0001950547,0.0005247068,0.0001128198,0.0002901398,0.0002895714],"domain_scores_gemma":[0.998674,0.0003892832,0.0005065276,0.00005804391,0.0002059262,0.0001661919],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0008155851,0.0001015493,0.00185684,0.0001393022,0.000228482,0.002212838,0.0001082342,0.000009335155,0.9365013,0.00007697416,0.0008376855,0.05711184],"study_design_scores_gemma":[0.00713834,0.0009286008,0.6720898,0.0002910012,0.0007584215,0.02822177,0.0002878788,0.0001465551,0.2880434,0.0001755525,0.001747758,0.0001709551],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911606,0.001650295,0.005598804,0.000281675,0.0008656335,0.0002630784,0.000003329221,0.000008957609,0.0001675673],"genre_scores_gemma":[0.9980002,0.001001316,0.0004524628,0.0002933537,0.0002011497,0.000001308732,4.637206e-7,0.00001637681,0.00003338286],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6702329,"threshold_uncertainty_score":0.3945417,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01724167600810244,"score_gpt":0.3026697161286305,"score_spread":0.285428040120528,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}