{"id":"W2140542886","doi":"10.1091/mbc.e12-01-0055","title":"UNC-89 (obscurin) binds to MEL-26, a BTB-domain protein, and affects the function of MEI-1 (katanin) in striated muscle of<i>Caenorhabditis elegans</i>","year":2012,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of General Medical Sciences; Canadian Institutes of Health Research; University of California, San Diego; National Institutes of Health; Emory University","keywords":"Caenorhabditis elegans; Biology; Cell biology; Ubiquitin; Sarcomere; Myosin; Cullin; Signal transducing adaptor protein; Microtubule; Ubiquitin ligase; Mutant; Proteasome; Molecular biology; Myocyte; Biochemistry; Signal transduction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000495787,0.0005424744,0.0001184118,0.0001673278,0.0002284614,0.0002037968,0.000300869,0.0002800577,0.001982626],"category_scores_gemma":[0.00005309255,0.0002006228,0.0002199014,0.00007206002,0.0002187562,0.0001085485,0.0002542138,0.0003744006,0.00070326],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004212584,"about_ca_system_score_gemma":0.00009498461,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001399095,"about_ca_topic_score_gemma":0.002118474,"domain_scores_codex":[0.9999024,0.000008468333,0.00000897115,0.00002858224,0.00003425096,0.00001745382],"domain_scores_gemma":[0.9999188,0.000006747626,0.00003483294,0.000006196589,0.000003553884,0.0000298923],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002035702,0.000006711676,0.0001502324,0.00001101187,0.000003830212,0.00005081072,0.000002365036,0.00002274573,0.9994893,0.0000234431,0.00002189347,0.00019729],"study_design_scores_gemma":[0.00001305779,0.0001261445,0.02066145,0.000007813926,0.0000181872,0.0007683643,0.00001844759,0.0007483456,0.9740263,0.0000198498,0.003586793,0.000005183807],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958475,0.0007643795,0.001073558,0.00006692488,0.00002090589,0.00001100374,0.0004150175,0.00008215847,0.001718664],"genre_scores_gemma":[0.9937424,0.0003955105,0.00098724,0.00004506608,0.000004546753,0.00001207332,0.0007460419,0.00002352407,0.004043656],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001982626,"threshold_uncertainty_score":0.006632566,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004219057915591427,"score_gpt":0.2013163282077169,"score_spread":0.1970972702921254,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}