{"id":"W2140577781","doi":"10.1152/ajpheart.00196.2006","title":"Novel role for K+-dependent Na+/Ca2+exchangers in regulation of cytoplasmic free Ca2+and contractility in arterial smooth muscle","year":2006,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health; National Institute for Health and Care Research; American Heart Association","keywords":"Extracellular; Vascular smooth muscle; Phenylephrine; Chemistry; Mesenteric arteries; Contractility; Contraction (grammar); Plasma membrane Ca2+ ATPase; Internal medicine; Endocrinology; Biochemistry; Biology; ATPase; Artery; Medicine; Smooth muscle; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001057826,0.0007700491,0.002181123,0.0006831024,0.0003299472,0.00004903224,0.0006413684,0.0004868747,0.000192604],"category_scores_gemma":[0.0003579821,0.0006954272,0.0005160959,0.0006103836,0.001880788,0.0006032991,0.0002236148,0.0009975216,0.00001416265],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002381084,"about_ca_system_score_gemma":0.0003014236,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000957266,"about_ca_topic_score_gemma":0.0000368999,"domain_scores_codex":[0.9938562,0.001057767,0.001905871,0.001404255,0.000548537,0.00122738],"domain_scores_gemma":[0.9964686,0.0009538326,0.001269979,0.0006950647,0.0002789779,0.000333566],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001196802,0.0006327968,0.0007308722,0.00009007048,0.00005301457,0.000002906026,0.002342963,0.154202,0.8395376,0.00009389409,0.0004280011,0.0006890278],"study_design_scores_gemma":[0.01650465,0.00423211,0.5347649,0.0003569177,0.0002489797,0.0003851413,0.01128565,0.3795407,0.03745708,0.009671094,0.00347697,0.002075778],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977245,0.0001965672,0.00004584801,0.0005371839,0.0003631213,0.0007883491,0.0002672279,0.00003462924,0.000042607],"genre_scores_gemma":[0.9974599,0.0001031585,0.0002188157,0.0009165002,0.001067133,0.00006328107,0.00005276416,0.00008489024,0.00003352648],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8020805,"threshold_uncertainty_score":0.9995497,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01351560474567026,"score_gpt":0.2370047177246146,"score_spread":0.2234891129789444,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}