{"id":"W2140599899","doi":"10.1139/bcb-2014-0075","title":"Profibrogenic phenotype in caveolin-1 deficiency via differential regulation of STAT-1/3 proteins","year":2014,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Caveolin-1 and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":true,"has_abstract":true,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; Ajou University","keywords":"STAT3; STAT protein; STAT1; Caveolin 1; Downregulation and upregulation; Fibrosis; Biology; Cancer research; Signal transduction; Cell biology; stat; Transforming growth factor; Protein tyrosine phosphatase; JAK-STAT signaling pathway; Cell growth; Pulmonary fibrosis; Tyrosine kinase; Medicine; Internal medicine; Gene; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":{"nature":"Retraction","reason":"Duplication of/in Image;Investigation by Company/Institution;Original Data and/or Images not Provided and/or not Available;Unreliable Image;","date":"4/11/2023 0:00","openalex_flagged":true},"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001167779,0.0002551944,0.0001663472,0.0002817597,0.0001240291,0.0002092349,0.0001183388,0.0002550057,0.0008719566],"category_scores_gemma":[0.00008600729,0.0001130852,0.0001929161,0.0001532355,0.0003220193,0.0001355614,0.0001432618,0.0003725294,0.000198322],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002581609,"about_ca_system_score_gemma":0.0001602415,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003859981,"about_ca_topic_score_gemma":0.0007024066,"domain_scores_codex":[0.9998888,0.00001967596,0.00001168121,0.00002562647,0.00002773579,0.00002644065],"domain_scores_gemma":[0.9998971,0.00001429657,0.00003917363,0.000008750377,0.000008225049,0.00003243272],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008344291,0.000005827218,0.0002384339,0.00001268676,0.000002077572,0.00006882015,0.000005192878,0.00002059586,0.9991269,0.00007410115,0.00001335997,0.0003486385],"study_design_scores_gemma":[0.00004371465,0.0002598886,0.03658244,0.00001048015,0.00003831767,0.002688094,0.00005012501,0.001710226,0.9558418,0.00038818,0.002375253,0.00001154364],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961445,0.001115468,0.001697167,0.00008691807,0.00001642741,0.000009376245,0.0002382367,0.00006501257,0.0006268444],"genre_scores_gemma":[0.9977764,0.0003986784,0.000759222,0.00004650803,0.00000527581,0.0000107663,0.0002700666,0.0000123949,0.000720561],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008719566,"threshold_uncertainty_score":0.002916992,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004301551676747244,"score_gpt":0.2043525651980102,"score_spread":0.2000510135212629,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}