{"id":"W2140675020","doi":"10.18433/j38c88","title":"The Decrease in Farnesoid X Receptor, Pregnane X Receptor and Constitutive Androstane Receptor in the Liver after Intestinal Ischemia-Reperfusion","year":2012,"lang":"en","type":"article","venue":"Journal of Pharmacy & Pharmaceutical Sciences","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Nakatomi Foundation","keywords":"Pregnane X receptor; Constitutive androstane receptor; Farnesoid X receptor; Pregnane; Nuclear receptor; Internal medicine; Multidrug resistance-associated protein 2; Receptor; Endocrinology; Blot; Chemistry; Biology; Biochemistry; Medicine; Transporter; Transcription factor; Gene; ATP-binding cassette transporter","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002270808,0.0004553254,0.0005066724,0.0003571623,0.0001534735,0.000277783,0.0001172338,0.0002940409,0.002125263],"category_scores_gemma":[0.0001922372,0.0001669631,0.0005002169,0.0002126236,0.0003662242,0.0003810506,0.000141171,0.0005929501,0.0004393637],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002526507,"about_ca_system_score_gemma":0.000181573,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003191646,"about_ca_topic_score_gemma":0.0003502344,"domain_scores_codex":[0.9998015,0.00002925391,0.00002255257,0.00004638692,0.00005205871,0.00004826624],"domain_scores_gemma":[0.9998279,0.00001468632,0.00007510778,0.00001530275,0.00002651954,0.00004040501],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001101927,0.00006027382,0.001780765,0.0002058478,0.00002413045,0.0002275368,0.00004933712,0.00003883511,0.9933477,0.0000583892,0.00006754843,0.003037608],"study_design_scores_gemma":[0.0001037353,0.002202706,0.08392749,0.0000369826,0.0001831553,0.001949431,0.0003103423,0.0006718128,0.9070556,0.0001548714,0.003380702,0.00002319261],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9805119,0.01448859,0.003220635,0.0002033779,0.00008034975,0.00002833709,0.0002892714,0.0001622655,0.001015427],"genre_scores_gemma":[0.9887207,0.004805798,0.001519777,0.0001135822,0.00004655328,0.00006800102,0.0006055469,0.00002692864,0.004093037],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002125263,"threshold_uncertainty_score":0.007109702,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1073705201871103,"score_gpt":0.4361081637680932,"score_spread":0.328737643580983,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}