{"id":"W2140733766","doi":"10.1093/mutage/geq085","title":"Reflections on the development of micronucleus assays","year":2010,"lang":"en","type":"article","venue":"Mutagenesis","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"Centre International de Recherche sur le Cancer","keywords":"Micronucleus test; Biology; Medicine; Toxicity","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.06458595,0.002098917,0.001382953,0.003313783,0.00128246,0.006612583,0.006087906,0.007694849,0.006096325],"category_scores_gemma":[0.07040449,0.001589102,0.002109898,0.001420784,0.01110452,0.01113169,0.004795629,0.03862815,0.006713519],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004228418,"about_ca_system_score_gemma":0.004974805,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003097153,"about_ca_topic_score_gemma":0.004226254,"domain_scores_codex":[0.9524724,0.0155093,0.003930267,0.003066464,0.02381777,0.001203803],"domain_scores_gemma":[0.8894144,0.03813262,0.005319299,0.005437829,0.05677869,0.004917118],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003045923,0.0003368997,0.001125484,0.00261884,0.0001252662,0.0003721439,0.001379856,0.0009640557,0.01252521,0.05988805,0.5525643,0.3677953],"study_design_scores_gemma":[0.00001791239,0.0001509201,0.0003350778,0.0005616101,0.00001926978,0.0003076859,0.0001704089,0.0001027367,0.005860969,0.007729772,0.9846705,0.00007304522],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001567199,0.2258,0.06683466,0.5831078,0.09446094,0.000366996,0.0004266719,0.0007118601,0.02672389],"genre_scores_gemma":[0.02019198,0.342724,0.1926129,0.2743121,0.06496784,0.001051303,0.0008858486,0.001530745,0.1017233],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.06458595,"threshold_uncertainty_score":0.3415672,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03025173002003488,"score_gpt":0.3166423014699582,"score_spread":0.2863905714499233,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}