{"id":"W2140735560","doi":"10.1371/journal.pone.0003220","title":"Fibrotic Myofibroblasts Manifest Genome-Wide Derangements of Translational Control","year":2008,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","field":"Medicine","cited_by":106,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Heart, Lung, and Blood Institute; Vetenskapsrådet; Knut och Alice Wallenbergs Stiftelse","keywords":"Myofibroblast; Idiopathic pulmonary fibrosis; Biology; Pathology; Cell biology; Cancer research; Fibrosis; Epithelial–mesenchymal transition; Extracellular matrix; Immunology; Medicine; Lung; Gene; Genetics; Internal medicine; Downregulation and upregulation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001390039,0.0002413243,0.0001927135,0.0003729929,0.000141598,0.0002142923,0.00008510383,0.0002763064,0.001040228],"category_scores_gemma":[0.0001351067,0.00009869014,0.0001508226,0.0002500692,0.0002446794,0.0001280142,0.0001412006,0.0002348992,0.0002750635],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001164952,"about_ca_system_score_gemma":0.0000733804,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001882594,"about_ca_topic_score_gemma":0.0003075991,"domain_scores_codex":[0.999887,0.00001680336,0.00001272853,0.00003107636,0.00002748737,0.00002478954],"domain_scores_gemma":[0.9997849,0.00003886635,0.0001031356,0.00002712713,0.00001850051,0.00002761509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000056229,0.00000851313,0.0017263,0.00001822338,0.000004339763,0.000106568,0.00001741716,0.00001273509,0.9974167,0.00002959951,0.00002032091,0.0005830237],"study_design_scores_gemma":[0.00001899853,0.0005948993,0.2339857,0.00001469265,0.00005222511,0.004621554,0.0002171214,0.0005714112,0.7560983,0.000234982,0.003578998,0.0000110582],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960287,0.001342743,0.001403397,0.00004405029,0.000009191858,0.00001855513,0.0005407786,0.00006003604,0.0005525784],"genre_scores_gemma":[0.9965273,0.0006174706,0.001315951,0.00004451783,0.00001144867,0.00003781849,0.0008506094,0.00001091023,0.000584024],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001040228,"threshold_uncertainty_score":0.003479898,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03169449058755442,"score_gpt":0.2159766688481924,"score_spread":0.1842821782606379,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}