{"id":"W2140740264","doi":"10.1158/1541-7786.mcr-07-0294","title":"Transforming Growth Factor-β1, Transforming Growth Factor-β2, and Transforming Growth Factor-β3 Enhance Ovarian Cancer Metastatic Potential by Inducing a Smad3-Dependent Epithelial-to-Mesenchymal Transition","year":2008,"lang":"en","type":"article","venue":"Molecular Cancer Research","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":111,"is_retracted":false,"has_abstract":true,"ca_institutions":"Science North","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institutes of Health","keywords":"Transforming growth factor; Epithelial–mesenchymal transition; Cancer research; Ovarian cancer; Carcinogenesis; Biology; Small interfering RNA; Metastasis; Cancer cell; microRNA; Transforming growth factor beta; Transfection; Cancer; Endocrinology; Cell culture; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001338524,0.0002761305,0.0001924793,0.0002283952,0.00009522957,0.0001954774,0.00007993076,0.0001386734,0.0009326569],"category_scores_gemma":[0.00009150674,0.0001038138,0.0002717291,0.0001184139,0.0001881385,0.0001144216,0.0001333746,0.0003759877,0.0001769394],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001199783,"about_ca_system_score_gemma":0.0001961954,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004028983,"about_ca_topic_score_gemma":0.0008082122,"domain_scores_codex":[0.9999318,0.00001440005,0.000005234507,0.000005930128,0.00001964867,0.00002299362],"domain_scores_gemma":[0.999925,0.0000175603,0.00001948641,0.000005361318,0.000006077469,0.0000265166],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003126007,0.0001126128,0.0003795075,0.0000456782,0.000008258858,0.00005358198,0.00001777869,0.00006875838,0.9967052,0.00006714074,0.00005052197,0.002178214],"study_design_scores_gemma":[0.0001405215,0.001596504,0.0149732,0.000007887149,0.00004013891,0.0004412765,0.00006528729,0.001610704,0.9771135,0.0001215572,0.003884248,0.000005202876],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955771,0.001600653,0.001026307,0.00009624106,0.00002169327,0.00003436955,0.0001084078,0.0000572624,0.001477889],"genre_scores_gemma":[0.9960936,0.001120194,0.001387154,0.00007370195,0.00001131003,0.00003277145,0.0001955172,0.000009901572,0.001075948],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009326569,"threshold_uncertainty_score":0.003120065,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02882556907520099,"score_gpt":0.321598381548112,"score_spread":0.292772812472911,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}