{"id":"W2140740264","doi":"10.1158/1541-7786.mcr-07-0294","title":"Transforming Growth Factor-β1, Transforming Growth Factor-β2, and Transforming Growth Factor-β3 Enhance Ovarian Cancer Metastatic Potential by Inducing a Smad3-Dependent Epithelial-to-Mesenchymal Transition","year":2008,"lang":"en","type":"article","venue":"Molecular Cancer Research","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":111,"is_retracted":false,"has_abstract":true,"ca_institutions":"Science North","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institutes of Health","keywords":"Transforming growth factor; Epithelial–mesenchymal transition; Cancer research; Ovarian cancer; Carcinogenesis; Biology; Small interfering RNA; Metastasis; Cancer cell; microRNA; Transforming growth factor beta; Transfection; Cancer; Endocrinology; Cell culture; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000652134,0.0009148043,0.0008235701,0.0005910706,0.001070592,0.0002222598,0.0008362495,0.0004815429,0.000245152],"category_scores_gemma":[0.0001657444,0.00094183,0.0004462705,0.0008093047,0.0004366869,0.0001549748,0.0001214728,0.001059955,0.00001256198],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003890886,"about_ca_system_score_gemma":0.001139599,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006157465,"about_ca_topic_score_gemma":0.0008107129,"domain_scores_codex":[0.9925707,0.0006139912,0.0009823544,0.00185345,0.001975049,0.002004453],"domain_scores_gemma":[0.9975098,0.00008908535,0.0001576658,0.0005655576,0.0007436986,0.0009341305],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007688189,0.0002108302,0.000613087,0.0005217687,0.0004926007,0.0002250134,0.00518335,0.0001626571,0.9838284,0.00002955416,0.0000673281,0.007896567],"study_design_scores_gemma":[0.002223961,0.0005965143,0.001285993,0.0003199547,0.0001333144,0.00008236403,0.0004069993,0.0001018814,0.9930142,0.00008739645,0.000632373,0.001115116],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9122939,0.00488561,0.07779389,0.0007951356,0.0002363882,0.001937473,0.001873013,0.00008923961,0.00009536386],"genre_scores_gemma":[0.9946483,0.002628769,0.0005619218,0.0003188621,0.0003436817,0.0008016238,0.0002773719,0.0002469846,0.000172522],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08235437,"threshold_uncertainty_score":0.9993032,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02882556907520099,"score_gpt":0.321598381548112,"score_spread":0.292772812472911,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}