{"id":"W2140770193","doi":"10.1021/ol060110w","title":"Enantioselective MSPV Reduction of Ketimines Using 2-Propanol and (BINOL)Al<sup>III</sup>","year":2006,"lang":"en","type":"article","venue":"Organic Letters","topic":"Asymmetric Hydrogenation and Catalysis","field":"Chemistry","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; Natural Sciences and Engineering Research Council of Canada; Amgen","keywords":"Enantioselective synthesis; Chemistry; Enantiomer; Propanol; Chelation; Bicyclic molecule; Selectivity; Organic chemistry; Medicinal chemistry; Combinatorial chemistry; Catalysis; Ethanol","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000731,0.0001467668,0.0001967891,0.0001608407,0.00009473273,0.00002427745,0.00009826676,0.00007913238,0.0002719495],"category_scores_gemma":[0.00003654996,0.0001440228,0.00006468905,0.0005628431,0.00009197551,0.000129154,0.00003664254,0.0001084243,0.000009316885],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001193365,"about_ca_system_score_gemma":0.0000320163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002271405,"about_ca_topic_score_gemma":0.000002649942,"domain_scores_codex":[0.9990228,0.00001740833,0.0002633841,0.0002831968,0.000218831,0.000194394],"domain_scores_gemma":[0.9995064,0.00002602248,0.0001624313,0.0001983261,0.00006774002,0.00003907396],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001079378,0.00004081781,0.0007862882,0.00002906568,0.00005877432,0.000003625596,0.0001907923,0.0001189408,0.9962926,0.00002261173,0.001380868,0.001064853],"study_design_scores_gemma":[0.000540592,0.00000633814,0.0002138961,0.00001693529,0.00009864403,0.00006803822,0.0002901381,0.00173929,0.9963527,0.0000182846,0.0004844381,0.0001707124],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974657,0.0001383992,0.0008163337,0.0007914348,0.00003004228,0.00005053366,0.000006609269,0.00005903141,0.0006418949],"genre_scores_gemma":[0.9990919,0.00001707741,0.0002697926,0.0001845912,0.0001486483,0.000003228614,0.00003271949,0.00002792742,0.0002241351],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001626159,"threshold_uncertainty_score":0.5873078,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007219277612563872,"score_gpt":0.2057088580007191,"score_spread":0.1984895803881553,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}