{"id":"W2140782967","doi":"10.2337/db09-1706","title":"Natural Killer Cells From Children With Type 1 Diabetes Have Defects in NKG2D-Dependent Function and Signaling","year":2011,"lang":"en","type":"article","venue":"Diabetes","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; BC Children's Hospital; University of British Columbia","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; Michael Smith Health Research BC; Child and Family Research Institute; Canadian Diabetes Association; American College of Rheumatology Research and Education Foundation","keywords":"NKG2D; Natural killer cell; Interleukin 12; Immunology; Interleukin 21; Biology; Endocrinology; Internal medicine; Medicine; Cytotoxic T cell; Immune system; T cell; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001773879,0.0006093616,0.0003075721,0.0003718662,0.0002429672,0.0004068371,0.0001999606,0.0002824331,0.002023967],"category_scores_gemma":[0.0004607756,0.0001225217,0.0002440045,0.0003917194,0.0002530125,0.0002233959,0.0002869468,0.000473285,0.0003609997],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002370797,"about_ca_system_score_gemma":0.0002098983,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009751084,"about_ca_topic_score_gemma":0.0008835958,"domain_scores_codex":[0.9997582,0.00002144824,0.00003436845,0.0000847644,0.00005956315,0.00004167046],"domain_scores_gemma":[0.9997362,0.00004278386,0.0001384989,0.00001365537,0.00002758642,0.00004131292],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001282257,0.0001853741,0.7694641,0.0003690994,0.0001091493,0.006912076,0.000527246,0.0003259171,0.1900086,0.000243622,0.001142951,0.02942962],"study_design_scores_gemma":[0.00007683563,0.0005800584,0.9286462,0.00008080984,0.0001409916,0.03349488,0.0006350515,0.0002349236,0.03010833,0.0001496563,0.005837751,0.00001444692],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997343,0.001113355,0.0003829781,0.00007249121,0.00001621965,0.00001376952,0.0005192003,0.00002742049,0.0005116478],"genre_scores_gemma":[0.9964002,0.001179976,0.0007298796,0.00008858422,0.00002560212,0.00002272294,0.0009736347,0.00001294876,0.0005662995],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002023967,"threshold_uncertainty_score":0.006770849,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008017110210188581,"score_gpt":0.1802768329388562,"score_spread":0.1722597227286676,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}