{"id":"W2140782967","doi":"10.2337/db09-1706","title":"Natural Killer Cells From Children With Type 1 Diabetes Have Defects in NKG2D-Dependent Function and Signaling","year":2011,"lang":"en","type":"article","venue":"Diabetes","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; BC Children's Hospital; University of British Columbia","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; Michael Smith Health Research BC; Child and Family Research Institute; Canadian Diabetes Association; American College of Rheumatology Research and Education Foundation","keywords":"NKG2D; Natural killer cell; Interleukin 12; Immunology; Interleukin 21; Biology; Endocrinology; Internal medicine; Medicine; Cytotoxic T cell; Immune system; T cell; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00009371008,0.0001708242,0.0001982482,0.000119699,0.00008837562,0.00001983392,0.00006853976,0.0001493988,0.001113567],"category_scores_gemma":[0.0000210458,0.0001368704,0.00003465098,0.00007398703,0.00007316729,0.0001832628,0.00003796405,0.0003094093,0.0002858402],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002476141,"about_ca_system_score_gemma":0.00001117295,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001686376,"about_ca_topic_score_gemma":0.00003761583,"domain_scores_codex":[0.9991332,0.0001041144,0.0001709719,0.0002810863,0.00002990257,0.0002807139],"domain_scores_gemma":[0.9996303,0.00008217921,0.00008237053,0.0001415455,0.00004683219,0.00001679466],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001083721,0.00006087059,0.408883,0.000003592562,0.0001503304,3.068251e-7,0.000243915,0.000002666451,0.5891057,0.000009845411,0.0005291257,0.0009022795],"study_design_scores_gemma":[0.0008671427,0.0002904406,0.3969864,0.00004416798,0.0000576388,7.50238e-7,0.0001720135,0.00001373067,0.6007541,0.00006933515,0.0005665151,0.0001777311],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925519,0.003475843,0.000005840798,0.000007509077,0.003286978,0.000158553,0.00000204138,0.00005498104,0.0004564132],"genre_scores_gemma":[0.9980454,0.00003021459,0.00003103193,0.0002260073,0.0000316548,0.00001338705,0.0001758941,0.00001896043,0.001427435],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01189653,"threshold_uncertainty_score":0.9997995,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008017110210188581,"score_gpt":0.1802768329388562,"score_spread":0.1722597227286676,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}