{"id":"W2140832617","doi":"10.1200/jco.2014.57.3055","title":"Molecular Testing for Selection of Patients With Lung Cancer for Epidermal Growth Factor Receptor and Anaplastic Lymphoma Kinase Tyrosine Kinase Inhibitors: American Society of Clinical Oncology Endorsement of the College of American Pathologists/International Association for the Study of Lung Cancer/Association for Molecular Pathology Guideline","year":2014,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":290,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"International Association for the Study of Lung Cancer","keywords":"Medicine; Guideline; Anaplastic lymphoma kinase; Lung cancer; Oncology; Epidermal growth factor receptor; Internal medicine; Cancer; Family medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01678255,0.0005256177,0.0009280909,0.002724196,0.001138285,0.002545465,0.002365624,0.006732463,0.004122257],"category_scores_gemma":[0.05408208,0.0004273709,0.002027758,0.002062468,0.001357822,0.001667976,0.001735271,0.006372519,0.003050737],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002027516,"about_ca_system_score_gemma":0.01621335,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01144116,"about_ca_topic_score_gemma":0.03062657,"domain_scores_codex":[0.9828572,0.006717426,0.003221119,0.0008392383,0.005475095,0.000889896],"domain_scores_gemma":[0.9488537,0.01369318,0.004589892,0.001305227,0.02925812,0.002299818],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007300235,0.000139225,0.006369059,0.002440119,0.0001172517,0.0005206283,0.0003407084,0.0003999731,0.001433295,0.005133529,0.798097,0.184936],"study_design_scores_gemma":[0.0002728502,0.0002461578,0.01305774,0.02012307,0.0004262669,0.002004706,0.0004920443,0.0008035162,0.001730127,0.007820325,0.9529247,0.00009847782],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"methods","genre_scores_codex":[0.0125983,0.1089749,0.0276032,0.647191,0.02220401,0.004534152,0.00633352,0.0007639307,0.169797],"genre_scores_gemma":[0.1314846,0.1697574,0.1459735,0.4774956,0.01415505,0.006001488,0.01804661,0.000477536,0.03660834],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.01678255,"threshold_uncertainty_score":0.08875567,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03833756373049924,"score_gpt":0.4406086431182212,"score_spread":0.4022710793877219,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}