{"id":"W2140875437","doi":"10.1084/jem.20140455","title":"CCDC88B is a novel regulator of maturation and effector functions of T cells during pathological inflammation","year":2014,"lang":"en","type":"article","venue":"The Journal of Experimental Medicine","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University and Génome Québec Innovation Centre","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Regulator; Effector; Inflammation; Pathological; Cell biology; Negative regulator; Biology; Immunology; Medicine; Pathology; Signal transduction; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001077648,0.0003045572,0.000320506,0.000307247,0.0001546841,0.0001732831,0.0002083363,0.0003411194,0.000821517],"category_scores_gemma":[0.0001364685,0.0001519138,0.0001751053,0.0002414281,0.0001729775,0.00005458907,0.0001516303,0.0002561124,0.0001999376],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002132721,"about_ca_system_score_gemma":0.000158195,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006251587,"about_ca_topic_score_gemma":0.000760696,"domain_scores_codex":[0.9998931,0.00001568506,0.000006427997,0.00003649838,0.00002830456,0.00002010717],"domain_scores_gemma":[0.9999163,0.00001365809,0.00003593839,0.000006602424,0.000007222495,0.00002031495],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001912564,0.00001632751,0.002688658,0.00003659485,0.00001246871,0.0001849104,0.000008492883,0.0001098539,0.9947609,0.00004891686,0.00006258531,0.001879009],"study_design_scores_gemma":[0.0002153215,0.0007848951,0.2838685,0.00003759406,0.000209721,0.005861082,0.00007542645,0.005718162,0.6924447,0.0002263902,0.01053673,0.00002147877],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941908,0.001364982,0.002773362,0.00008234617,0.000008443199,0.00002942453,0.0008922109,0.00007831605,0.0005801568],"genre_scores_gemma":[0.9947814,0.0004649775,0.002445798,0.00007863823,0.000006148699,0.00003269428,0.001557951,0.00001698412,0.0006153774],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000821517,"threshold_uncertainty_score":0.002748311,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009541286958098085,"score_gpt":0.2383025875693291,"score_spread":0.228761300611231,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}