{"id":"W2140906093","doi":"10.1111/j.1469-1809.2011.00668.x","title":"A Replication Study of the IRS1, CAPN10, TCF7L2, and PPARG Gene Polymorphisms Associated with Type 2 Diabetes in Two Different Populations of Mexico","year":2011,"lang":"en","type":"article","venue":"Annals of Human Genetics","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Instituto Mexicano del Seguro Social","keywords":"TCF7L2; Peroxisome proliferator-activated receptor gamma; Type 2 diabetes; Single-nucleotide polymorphism; Genetics; Biology; Type 2 Diabetes Mellitus; Internal medicine; Diabetes mellitus; Gene; Genotype; Endocrinology; Medicine; Peroxisome proliferator-activated receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001325117,0.000121278,0.0002078825,0.00006146229,0.0000405741,0.000003074407,0.0001809493,0.00006818705,0.000007224341],"category_scores_gemma":[0.00006299153,0.00008940737,0.00003427333,0.0001494442,0.0001187451,0.000003030503,0.0001018433,0.00006046692,7.78443e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000488182,"about_ca_system_score_gemma":0.00002377472,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009480222,"about_ca_topic_score_gemma":0.0005422941,"domain_scores_codex":[0.999059,0.0001120377,0.0003243798,0.0002305898,0.0001370585,0.0001369571],"domain_scores_gemma":[0.9989132,0.000007077892,0.0003207962,0.0005334069,0.0001910703,0.00003444298],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002069395,0.0003689305,0.4991247,0.000004039108,0.00006447863,5.854377e-8,0.0003171654,0.00002238815,0.4999835,0.000009145091,0.00001704952,0.00006778543],"study_design_scores_gemma":[0.0003011157,0.0006591724,0.4323231,0.00001462218,0.00002016738,1.806649e-7,0.0000595882,0.00001470342,0.5664767,0.00007187386,0.000001821168,0.00005699797],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99896,0.000626725,0.000002386429,0.0000162493,0.00002771524,0.0002980295,0.00001920598,0.000003132756,0.00004654149],"genre_scores_gemma":[0.9997505,0.00007282389,0.00004971313,0.00002600459,0.00001217024,0.00001373597,0.00003688663,0.00001736852,0.00002078855],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06680165,"threshold_uncertainty_score":0.3645927,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07343149739810038,"score_gpt":0.3181278339311928,"score_spread":0.2446963365330924,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}