{"id":"W2140917992","doi":"10.1016/j.canlet.2008.02.016","title":"In vivo validation of PAX2 as a target for renal cancer therapy","year":2008,"lang":"en","type":"article","venue":"Cancer Letters","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Children's Hospital; McGill University","funders":"Kidney Foundation of Canada; McGill University","keywords":"Cancer research; Gene knockdown; Cisplatin; Gene silencing; Small hairpin RNA; Cancer; In vivo; Apoptosis; Cell culture; Biology; Cancer cell; Targeted therapy; Transfection; Medicine; Chemotherapy; Internal medicine; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004296678,0.00009162197,0.0001126326,0.00003479124,0.0000318852,0.000002616087,0.00008883815,0.00008294048,0.00008818207],"category_scores_gemma":[0.000005630587,0.0000773885,0.00007647133,0.00007925843,0.00007322374,0.000004514014,0.000009648258,0.00005139513,8.899825e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003812005,"about_ca_system_score_gemma":0.0001215416,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003361151,"about_ca_topic_score_gemma":0.00001946849,"domain_scores_codex":[0.9994166,0.00001749899,0.0001423265,0.0001914027,0.00007683366,0.0001553518],"domain_scores_gemma":[0.9997443,0.000005067222,0.00007508757,0.0001072257,0.00003769928,0.00003062269],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002691093,0.00001382666,0.001799183,0.00001367137,0.00006065329,0.000002687764,0.0001202045,0.005642036,0.9501141,0.000004861824,0.0413539,0.0006058236],"study_design_scores_gemma":[0.0009004857,0.00009466991,0.0001886888,0.00002375849,0.000004985842,0.000003286939,0.000005358294,0.00002022431,0.8626639,0.00002088339,0.1359753,0.00009845041],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936487,0.002761058,0.0004197098,0.00245099,0.0002819691,0.000201221,0.00004106346,0.000003651863,0.0001916431],"genre_scores_gemma":[0.9860711,0.007317814,0.0001677525,0.004625941,0.0004300585,0.0002859589,0.00002859173,0.00002049765,0.001052339],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09462138,"threshold_uncertainty_score":0.3155811,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01266456411675408,"score_gpt":0.2703266934093089,"score_spread":0.2576621292925548,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}