{"id":"W2140917992","doi":"10.1016/j.canlet.2008.02.016","title":"In vivo validation of PAX2 as a target for renal cancer therapy","year":2008,"lang":"en","type":"article","venue":"Cancer Letters","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Children's Hospital; McGill University","funders":"Kidney Foundation of Canada; McGill University","keywords":"Cancer research; Gene knockdown; Cisplatin; Gene silencing; Small hairpin RNA; Cancer; In vivo; Apoptosis; Cell culture; Biology; Cancer cell; Targeted therapy; Transfection; Medicine; Chemotherapy; Internal medicine; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009072068,0.0004396302,0.0003658586,0.0004136825,0.0004515919,0.0006912141,0.0005153136,0.0007647029,0.005217068],"category_scores_gemma":[0.0003993393,0.0003033804,0.0003672113,0.0002354593,0.0004941793,0.0005900279,0.0002790619,0.001542991,0.001042419],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004989775,"about_ca_system_score_gemma":0.0004524968,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001108945,"about_ca_topic_score_gemma":0.001077748,"domain_scores_codex":[0.9996246,0.0001411613,0.00002211754,0.00005103912,0.00009463117,0.00006635719],"domain_scores_gemma":[0.9997848,0.0000826507,0.00002357718,0.00004404075,0.00003048025,0.00003447027],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006649691,0.0001591155,0.0002234057,0.00006945534,0.00001785515,0.00007935249,0.00003577386,0.0004184493,0.9933178,0.001355003,0.0003918498,0.00326688],"study_design_scores_gemma":[0.00009708821,0.0005465026,0.0005791022,0.000004712636,0.00002491836,0.0002424844,0.00004303992,0.00168762,0.9916915,0.0001879182,0.004890767,0.000004423989],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9442626,0.004096668,0.02687094,0.001822279,0.0004257271,0.0003251605,0.001446303,0.0003872225,0.02036314],"genre_scores_gemma":[0.9795222,0.001080025,0.007790244,0.0001671579,0.00005364589,0.0001534707,0.0009890274,0.0001036242,0.01014058],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005217068,"threshold_uncertainty_score":0.01745284,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01266456411675408,"score_gpt":0.2703266934093089,"score_spread":0.2576621292925548,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}