{"id":"W2140949230","doi":"10.1158/0008-5472.can-05-0217","title":"Targeted Inhibition of the KLF6 Splice Variant, KLF6 SV1, Suppresses Prostate Cancer Cell Growth and Spread","year":2005,"lang":"en","type":"article","venue":"Cancer Research","topic":"Kruppel-like factors research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":165,"is_retracted":false,"has_abstract":true,"ca_institutions":"Immunovaccine (Canada)","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Prostate cancer; Cancer research; Biology; Chromoplexy; Gene knockdown; Cancer; Cell growth; Metastasis; Prostate; Alternative splicing; Tumor suppressor gene; Tumor progression; Carcinogenesis; Gene isoform; Cell culture; Genetics; Gene; PCA3","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000491804,0.0001664957,0.0001679046,0.0000755878,0.0001790616,0.00004457571,0.0003797861,0.0001708635,0.0002918457],"category_scores_gemma":[0.0001728192,0.0001264883,0.00006317149,0.000349189,0.000452742,0.00002173096,0.0005646029,0.0003772643,0.000007479337],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001092335,"about_ca_system_score_gemma":0.0005940563,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004879106,"about_ca_topic_score_gemma":0.002479221,"domain_scores_codex":[0.9977148,0.000303689,0.00023003,0.0005064884,0.0006203213,0.0006246354],"domain_scores_gemma":[0.9986584,0.00005708944,0.00007288052,0.0004990405,0.0005551027,0.0001575086],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002075337,0.00007748541,0.007093733,0.0001972039,0.00003471192,0.000002598372,0.0002408696,0.00002857572,0.9805281,0.00003785743,0.01009253,0.001458868],"study_design_scores_gemma":[0.0006340511,0.0001475619,0.00539011,0.00006509059,0.000008939608,0.000003589762,0.0001395989,0.00002811031,0.9767831,0.00005337991,0.01660216,0.0001443128],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866534,0.008737137,0.00001544127,0.001738982,0.00008866307,0.0006720418,0.0003310327,0.000009012367,0.001754266],"genre_scores_gemma":[0.9872431,0.009995227,0.00006376009,0.00009171875,0.0003429462,0.0002520568,0.00004409334,0.00004027216,0.001926805],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006509631,"threshold_uncertainty_score":0.7375782,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02265521298183107,"score_gpt":0.3375404844316563,"score_spread":0.3148852714498253,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}