{"id":"W2140959656","doi":"10.1093/jnci/djs288","title":"Association Between Germline HOXB13 G84E Mutation and Risk of Prostate Cancer","year":2012,"lang":"en","type":"article","venue":"JNCI Journal of the National Cancer Institute","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's College Hospital; Sunnybrook Health Science Centre","funders":"Canadian Institutes of Health Research","keywords":"Prostate cancer; Odds ratio; Medicine; Confidence interval; Internal medicine; Germline mutation; Oncology; Prostate biopsy; Prostate; Cancer; Case-control study; Gynecology; Mutation; Genetics; Biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000485416,0.0002148031,0.0002461751,0.0007916259,0.0003743939,0.0003377031,0.0002583665,0.0004784963,0.002218826],"category_scores_gemma":[0.002610741,0.0002780225,0.0002366233,0.0005949592,0.0003805616,0.000163167,0.000236403,0.0005197189,0.0001228908],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000172755,"about_ca_system_score_gemma":0.0002500134,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008258274,"about_ca_topic_score_gemma":0.006491095,"domain_scores_codex":[0.9995182,0.0001593089,0.0000311451,0.0001224744,0.00008967759,0.00007924698],"domain_scores_gemma":[0.9986399,0.0004431208,0.0004145047,0.0001100449,0.0001139195,0.0002784506],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002057091,0.00003517788,0.9970505,0.000005149685,0.00006364664,0.0002777019,0.00003037151,0.00004183896,0.001126512,0.00002314848,0.00006729621,0.001072851],"study_design_scores_gemma":[0.0000107762,0.0001138556,0.998268,0.000003309334,0.00004216504,0.0009893045,0.00004103933,0.0002463401,0.0001409778,0.00003533981,0.000105463,0.000003380702],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992937,0.0001941401,0.0001040992,0.00004376879,0.000005865236,0.000003867693,0.00005215752,0.000005098198,0.0002973086],"genre_scores_gemma":[0.9996322,0.00006426618,0.0000974574,0.00001616884,0.00001005986,0.000001939708,0.00004454603,0.000001751318,0.0001315765],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008258274,"threshold_uncertainty_score":0.01642042,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02233668729244146,"score_gpt":0.3341546911111656,"score_spread":0.3118180038187242,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}