{"id":"W2140986784","doi":"10.1016/j.celrep.2015.04.065","title":"The eIF4E-Binding Protein 4E-T Is a Component of the mRNA Decay Machinery that Bridges the 5′ and 3′ Termini of Target mRNAs","year":2015,"lang":"en","type":"article","venue":"Cell Reports","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":80,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; McGill University; University of Toronto; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"P-bodies; Messenger RNA; EIF4E; Nonsense-mediated decay; Cell biology; Biology; Translation (biology); microRNA; RNA; Molecular biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000236823,0.0004195729,0.0003383849,0.0003103799,0.0005532146,0.0005299856,0.0002068181,0.000400804,0.001378531],"category_scores_gemma":[0.0002683646,0.0002003005,0.0005529849,0.0002579277,0.0003143426,0.0002968886,0.0003730946,0.000455465,0.0006330014],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005120187,"about_ca_system_score_gemma":0.0003360874,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005931745,"about_ca_topic_score_gemma":0.0006219219,"domain_scores_codex":[0.9998422,0.00002443861,0.00001048795,0.00004532917,0.00004489808,0.00003265803],"domain_scores_gemma":[0.999866,0.00001890832,0.00004561421,0.00001653989,0.00001987086,0.00003295114],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001249555,0.00002031752,0.001747777,0.00007568021,0.00001887159,0.0002012252,0.00001606831,0.0001658721,0.9918441,0.0004087472,0.0001180804,0.005258183],"study_design_scores_gemma":[0.00001387394,0.0001533555,0.01642388,0.00001102223,0.00001952692,0.001138666,0.00003908069,0.001278394,0.9699141,0.0002448206,0.01075195,0.00001127925],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9612479,0.008240411,0.02626202,0.0002615231,0.0001290113,0.00005416065,0.0004024882,0.0002966512,0.003105801],"genre_scores_gemma":[0.9759162,0.001720808,0.01615891,0.00008622619,0.00002804699,0.0000249725,0.0009437179,0.00003206588,0.005088971],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001378531,"threshold_uncertainty_score":0.004611671,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01824523883678296,"score_gpt":0.2565333173430768,"score_spread":0.2382880785062938,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}