{"id":"W2141042056","doi":"10.1128/aac.46.7.2116-2123.2002","title":"Enzymes Associated with Reductive Activation and Action of Nitazoxanide, Nitrofurans, and Metronidazole in <i>Helicobacter pylori</i>","year":2002,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Helicobacter pylori-related gastroenterology studies","field":"Medicine","cited_by":164,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Nitazoxanide; Nitrofuran; Metronidazole; Helicobacter pylori; Enzyme; Microbiology; Chemistry; Pharmacology; Biology; Medicine; Biochemistry; Antibiotics; Immunology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000165475,0.000490202,0.0002739574,0.000250161,0.0001021965,0.0002681068,0.0002220383,0.0003393154,0.0004633403],"category_scores_gemma":[0.000228136,0.0002352592,0.0003207643,0.0001756918,0.0001540462,0.0001838357,0.0001879187,0.0002525592,0.0003204147],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004361795,"about_ca_system_score_gemma":0.0002841793,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002138443,"about_ca_topic_score_gemma":0.001909686,"domain_scores_codex":[0.9997626,0.00003305934,0.00002359938,0.00005449259,0.00008406071,0.00004221722],"domain_scores_gemma":[0.9998437,0.00001911867,0.00005662066,0.00001741987,0.0000419149,0.00002113021],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004936747,0.00001545066,0.0007306665,0.00003041514,0.000004547396,0.0000270082,0.00001502215,0.00002805544,0.9979546,0.00004067214,0.00001223892,0.001091911],"study_design_scores_gemma":[0.000004830534,0.0001247711,0.01272478,0.000004211724,0.00001196404,0.0001854799,0.00002649272,0.0003794753,0.985563,0.00002331037,0.0009480231,0.000003601036],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895086,0.001720056,0.006844454,0.00009146257,0.00002427426,0.00006038462,0.0005525128,0.0001157133,0.001082502],"genre_scores_gemma":[0.9851412,0.00103785,0.009037292,0.00004703421,0.00001029712,0.00005302939,0.002105701,0.00003546409,0.002532147],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002138443,"threshold_uncertainty_score":0.004251957,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02090521210176747,"score_gpt":0.2444453469904313,"score_spread":0.2235401348886639,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}