{"id":"W2141042056","doi":"10.1128/aac.46.7.2116-2123.2002","title":"Enzymes Associated with Reductive Activation and Action of Nitazoxanide, Nitrofurans, and Metronidazole in <i>Helicobacter pylori</i>","year":2002,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Helicobacter pylori-related gastroenterology studies","field":"Medicine","cited_by":164,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Nitazoxanide; Nitrofuran; Metronidazole; Helicobacter pylori; Enzyme; Microbiology; Chemistry; Pharmacology; Biology; Medicine; Biochemistry; Antibiotics; Immunology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008086059,0.0001837067,0.0003601226,0.0001345755,0.00006352013,0.00001438003,0.00002567105,0.0001161139,0.00002731812],"category_scores_gemma":[0.00001966471,0.0001482554,0.00002276107,0.0001721499,0.0001953039,0.0001681773,0.00001853043,0.0001841679,6.288673e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004201489,"about_ca_system_score_gemma":0.000007351052,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009218656,"about_ca_topic_score_gemma":0.0000514135,"domain_scores_codex":[0.9991581,0.00004142228,0.00022135,0.0002684565,0.00009223839,0.0002183677],"domain_scores_gemma":[0.9996189,0.00003184107,0.0001256391,0.00008848026,0.00008025049,0.00005490159],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007734302,0.0004188702,0.893353,0.00006258939,0.0006913698,0.000007446847,0.002363272,9.383839e-7,0.09262782,0.000006811836,0.002179654,0.007514766],"study_design_scores_gemma":[0.006005724,0.0004862896,0.9389131,0.0002319679,0.0001055853,0.00003774854,0.0003254492,0.00005231397,0.05295489,0.000007922869,0.0007371409,0.0001418554],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947295,0.00008909059,0.00001742739,0.004723702,0.00003429016,0.0002700493,0.0000108927,0.00002071508,0.0001043699],"genre_scores_gemma":[0.9951926,0.002226267,0.0001075678,0.002249815,0.00003557865,0.000006215657,0.00001572159,0.00002272918,0.0001434598],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04556008,"threshold_uncertainty_score":0.6045681,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02090521210176747,"score_gpt":0.2444453469904313,"score_spread":0.2235401348886639,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}