{"id":"W2141091298","doi":"10.1128/ec.00077-08","title":"Heterotrimeric G-Protein Subunit Function in <i>Candida albicans</i> : both the α and β Subunits of the Pheromone Response G Protein Are Required for Mating","year":2008,"lang":"en","type":"article","venue":"Eukaryotic Cell","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Biotechnology Research Institute","funders":"National Research Council Canada; Canadian Institutes of Health Research","keywords":"Heterotrimeric G protein; Biology; Protein subunit; G protein; Pheromone; Candida albicans; Fungal protein; Function (biology); Gs alpha subunit; Genetics; Cell biology; Saccharomyces cerevisiae; Yeast; Gene; Signal transduction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009497013,0.0003395662,0.0001196752,0.0001480052,0.0001702236,0.0003555333,0.0003337869,0.0002740361,0.0006787941],"category_scores_gemma":[0.0000988282,0.00008805327,0.0001471959,0.0001237325,0.0002108213,0.000133515,0.0001883576,0.0004755246,0.0003861571],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005221409,"about_ca_system_score_gemma":0.0002747678,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001469629,"about_ca_topic_score_gemma":0.001346592,"domain_scores_codex":[0.9999285,0.00001070003,0.000006683653,0.00001288267,0.00002082932,0.00002038771],"domain_scores_gemma":[0.9999343,0.000008013893,0.00001771913,0.00001173828,0.000007801109,0.00002040771],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006056781,0.00001428619,0.0001518379,0.00001563461,0.000002034036,0.0000442108,0.000004214199,0.00004055146,0.9987451,0.000141554,0.00006044364,0.000719626],"study_design_scores_gemma":[0.00001779008,0.00008510425,0.004681437,0.000006217913,0.00001578859,0.0005633321,0.00001919188,0.0008374981,0.991448,0.00008006777,0.002241487,0.000003945247],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943832,0.001814432,0.001545363,0.0002380351,0.00003614816,0.0000133757,0.0003427425,0.0001205406,0.001506127],"genre_scores_gemma":[0.9964767,0.0005082241,0.001045807,0.00008048484,0.000007339668,0.0000141194,0.0004488592,0.00001847252,0.001399928],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001469629,"threshold_uncertainty_score":0.003788412,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0252556002747492,"score_gpt":0.2381371362284113,"score_spread":0.2128815359536621,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}