{"id":"W2141130828","doi":"10.4049/jimmunol.1202725","title":"Cytotoxic NKG2C+ CD4 T Cells Target Oligodendrocytes in Multiple Sclerosis","year":2013,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University; McGill University; Université de Montréal; Hôpital Notre-Dame; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research","keywords":"Cytotoxic T cell; Granzyme B; Perforin; CD8; Granzyme; Multiple sclerosis; Biology; Cell biology; Interleukin 21; Immunology; Myelin; Immune system; Chemistry; In vitro; Neuroscience; Central nervous system; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009947472,0.0004420166,0.0004063224,0.0004841058,0.0002500127,0.0002663671,0.0001508458,0.0004770662,0.001695202],"category_scores_gemma":[0.0001541992,0.0001554674,0.0001208396,0.0002014324,0.0003524695,0.0002394776,0.0002783628,0.0003293347,0.0003056262],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000261225,"about_ca_system_score_gemma":0.0001779838,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004948485,"about_ca_topic_score_gemma":0.0004432373,"domain_scores_codex":[0.9999064,0.00001925166,0.0000111452,0.0000231176,0.00002146853,0.00001859109],"domain_scores_gemma":[0.9999584,0.000006307328,0.000011266,0.00000432756,0.000006526444,0.00001310322],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001747351,0.0001409574,0.01479959,0.0003287274,0.00003169593,0.003773394,0.0001709817,0.000249226,0.9585876,0.0002908209,0.0004726121,0.01940707],"study_design_scores_gemma":[0.0007069905,0.003568307,0.3930739,0.0001912529,0.0003540612,0.06323157,0.0008847113,0.003383698,0.5106577,0.002915281,0.02097915,0.00005336443],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921253,0.005643019,0.0004887949,0.0001067567,0.0000173557,0.00001811439,0.00004143214,0.00005313346,0.001506099],"genre_scores_gemma":[0.9962335,0.001928057,0.0003978015,0.00006254755,0.00003416117,0.00002087175,0.00007156621,0.000006315663,0.001245192],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001695202,"threshold_uncertainty_score":0.005671084,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01878990087065797,"score_gpt":0.2060828954158796,"score_spread":0.1872929945452217,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}