{"id":"W2141135082","doi":"10.1128/aac.45.2.433-438.2001","title":"Mutant Prevention Concentrations of Fluoroquinolones for Clinical Isolates of <i>Streptococcus pneumoniae</i>","year":2001,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Pneumonia and Respiratory Infections","field":"Medicine","cited_by":314,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Royal University Hospital","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Bayer","keywords":"Gatifloxacin; Moxifloxacin; Streptococcus pneumoniae; Levofloxacin; Trovafloxacin; Microbiology; Sparfloxacin; Mutant; Minimum inhibitory concentration; Medicine; Antibiotics; Pharmacology; Ciprofloxacin; Biology; Ofloxacin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007536501,0.0003175209,0.0004461448,0.0004220297,0.0001493088,0.0006226467,0.0002321156,0.0005862092,0.0006700031],"category_scores_gemma":[0.004069106,0.0002234451,0.0002611087,0.0003065445,0.0002074532,0.0002998015,0.0002080824,0.0005795161,0.0002435784],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004113076,"about_ca_system_score_gemma":0.0003570647,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001300996,"about_ca_topic_score_gemma":0.001205375,"domain_scores_codex":[0.9987977,0.0003321669,0.0001889865,0.0001460068,0.0003910077,0.0001441262],"domain_scores_gemma":[0.9974818,0.0008791142,0.0008770471,0.0001941383,0.0003525401,0.0002153127],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006815754,0.0004254006,0.05596554,0.0004279183,0.0001334694,0.0002598921,0.0002541132,0.003723973,0.875926,0.0005718059,0.0009934052,0.0545028],"study_design_scores_gemma":[0.00007612696,0.007944263,0.07059858,0.00003160987,0.0001230655,0.0009562366,0.00007876672,0.003215132,0.9139594,0.0002161554,0.00276313,0.00003744244],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918969,0.002999342,0.002865235,0.0001771008,0.00002804978,0.00004283556,0.0005569704,0.0001520778,0.001281506],"genre_scores_gemma":[0.9967197,0.0002943106,0.002174705,0.00004718058,0.00001148404,0.00001859564,0.0004378012,0.0000125325,0.0002837581],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001300996,"threshold_uncertainty_score":0.003985763,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04553598527869962,"score_gpt":0.35835780988177,"score_spread":0.3128218246030704,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}